Chordoma: current status, problems, and future directions

MF Wedekind, BC Widemann, G Cote - Current Problems in Cancer, 2021 - Elsevier
Chordoma is a rare tumor that occurs along the axial spine in pediatrics and adults, with an
incidence of approximately 350 cases per year in the United States. While typically …

Chordoma: to know means to recognize

EN Karele, AN Paze - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Chordoma is a rare type of bone cancer characterized by its locally aggressive and
destructive behavior. Chordoma is located in one of the three primary regions: skull …

Definitive high-dose, proton-based radiation for unresected mobile spine and sacral chordomas

W Banfield, M Ioakeim-Ioannidou, S Goldberg… - Radiotherapy and …, 2022 - Elsevier
Abstract Background/Purpose Treatment of spine and sacral chordoma generally involves
surgical resection, usually in conjunction with radiation therapy. In certain locations …

The Use of Proton and Carbon Ion Radiation Therapy for Sarcomas

M Ioakeim-Ioannidou, M Rose, YL Chen… - Seminars in Radiation …, 2024 - Elsevier
The unique physical and biological characteristics of proton and carbon ions allow for
improved sparing of normal tissues, decreased integral dose to the body, and increased …

Cervical paraspinal chordoma: a literature review with a novel case report

R Jabbar, J Jankowski, A Pawełczyk, B Szmyd… - Journal of Clinical …, 2022 - mdpi.com
Chordomas are rare malignant neoplasms, accounting for 1–4% of all primary bone tumors.
Most spinal chordomas occur in the sacrococcygeal region and the base of the skull; …

Comprehensive review of cranial chordomas using national databases in the USA

MM Hulou, CR Garcia, SA Slone, A Dugan, F Lei… - Clinical Oncology, 2019 - Elsevier
Aims The management of cranial chordomas is controversial. We provide a comprehensive
review of the evolving patterns of care of cranial chordomas in the USA. Materials and …

Latest Developments in Targeted Biological Therapies in the Management of Chordoma and Chondrosarcoma

A Biczo, A Sahgal, JJ Verlaan… - Global Spine …, 2025 - journals.sagepub.com
Study Design Systematic review. Objectives The objective of this review paper was to
summarize targeted molecular therapy options for spinal chordoma and chondrosarcoma …

[HTML][HTML] Hematoporphyrin derivative-mediated photodynamic techniques for the diagnosis and treatment of chordoma

L Li, K Wei, M Liu, Q Wang, T Zeng, R Chen… - Photodiagnosis and …, 2024 - Elsevier
Background Chordoma is a rare congenital low-grade malignant tumor characterized by
infiltrative growth. It often tends to compress important intracranial nerves and blood vessels …

Long‐term outcomes of high dose carbon‐ion radiation therapy for unresectable upper cervical (C1‐2) chordoma

S Aoki, M Koto, H Ikawa, R Imai, O Tokuhiko… - Head & …, 2022 - Wiley Online Library
Background Chordoma is a rare, locally invasive neoplasm of the axial skeleton. Complete
resection is often difficult, especially for the upper‐cervical (C1‐2) spine. We evaluated the …

Dysregulation of noncoding RNA in chordoma; implications in identifying potential targets for novel therapeutic approaches

PK Ghosh, A Ghosh - Molecular Biology Reports, 2024 - Springer
Chordoma is a rare form of bone cancer develops in the spinal cord and skull. Instead of
conventional (radio/chemotherapies) and targeted therapies, the disease is associated with …