The optimal performance of the cardiovascular system, as well as the break-down of this
performance with disease, both involve complex biomechanical interactions between the …

Cerebral pulsatility reflects a balance between the transmission and damping of pulsatility in
the cerebrovasculature. Females experience greater cerebral pulsatility with aging, which …

Age-related changes in aortic biomechanics can impact the brain by reducing blood flow
and increasing pulsatile energy transmission. Clinical studies have shown that impaired …

Thoracic endovascular aortic repair (TEVAR) is a commonly performed operation for
patients with type B aortic dissection (TBAD). The goal of TEVAR is to cover the proximal …

This study investigates the physics of the longitudinal stretching-based wave pumping
mechanism, a novel extension of the traditional impedance pump. In its simplest form, an …

In-vitro models of the systemic circulation have gained a lot of interest for fundamental
understanding of cardiovascular dynamics and for applied hemodynamic research. In this …

Objective: The clinical significance of the wave intensity (WI) analysis for the diagnosis and
prognosis of the cardiovascular and cerebrovascular diseases is well-established. However …

Intrinsic Frequency (IF) is a systems-based approach that provides valuable information for
hemodynamic monitoring of the left ventricle (LV), the arterial system, and their coupling …

Aortic stiffness increases with age and is a robust predictor of brain pathology including
Alzheimer's and other dementias. Aging causes disproportionate stiffening of the aorta …

Type B aortic dissection is a life-threatening medical emergency that can result in rupture of
the aorta. Due to the complexity of patient-specific characteristics, only limited information on …