In 1996 the genome of Saccharomyces cerevisiae was published and marked the beginning
of a new era in fungal biology (1). Since then, rapid advancements in both sequencing …

The decreasing cost of sequencing and concomitant augmentation of publicly available
genomes have created an acute need for automated software to assess genomic …

Reconstruction of target genomes from sequence data produced by instruments that are
agnostic as to the species-of-origin may be confounded by contaminant DNA. Whether …

Background The study of microbiomes using whole-metagenome shotgun sequencing
enables the analysis of uncultivated microbial populations that may have important roles in …

The goal of many genome sequencing projects is to provide a complete representation of a
target genome (or genomes) as underpinning data for further analyses. However, it can be …

Objectives The introduction of metagenomic sequencing to diagnostic microbiology has
been hampered by slowness, cost and complexity. We explored whether MinION nanopore …

Tardigrades are meiofaunal ecdysozoans that are key to understanding the origins of
Arthropoda. Many species of Tardigrada can survive extreme conditions through …

Endophytes are known to play important roles in plant's health and productivity. In this study,
we investigated the root microbiome of tomato in association with infection by root knot …

Tardigrada, a phylum of meiofaunal organisms, have been at the center of discussions of the
evolution of Metazoa, the biology of survival in extreme environments, and the role of …

Abstract Background The NCBI BLAST suite has become ubiquitous in modern molecular
biology and is used for small tasks such as checking capillary sequencing results of single …