952 STRYNADKA & JAMES jected to high-resolution crystal structure analyses fall into two
general categories (Table 1). One group includes many extracellular enzymes and proteins …

Despite the 100 years that have elapsed since the discovery by Sidney Ringer of the vital
role for Ca2+ in the maintenance of cardiac contractility, the messenger function of Ca2+ has …

Stroke is the second leading cause of death and the third leading cause of disability
globally. Edema is a hallmark of stroke resulting from dysregulation of water homeostasis in …

This paper describes the distribution of structures stained with mono-and polyclonal
antibodies to the calcium-binding proteins calbindin D-28k and parvalbumin in the nervous …

The crystal structure of mammalian calmodulin has been refined at 2.2 Å (1 Å= 0.1 nm)
resolution using a restrained least-squares method. The final crystallographic R-factor …

The three-dimensional structure of calmodulin has been determined crystallographically at
3.0 Å resolution. The molecule consists of two globular lobes connected by a long exposed …

Because it is generally accepted that a high percentage of poorly motile or immotile sperm
will adversely affect male fertility, analysis of sperm motility is a central part of the evaluation …

The distribution Ca 2+-binding protein, parvalbumin (PV), containing neurons and their
colocalization with glutamic acid decar☐ ylase (GAD) were studied in the rat hippocampus …

Excess levels of circulating amino acids (AAs) play a causal role in specific human
pathologies, including obesity and type 2 diabetes. Moreover, obesity and diabetes are …

Intracellular Ca2+ is normally maintained at submicromolar levels but increases during
many forms of cellular stimulation. This increased Ca2+ binds to receptor proteins such as …