Immunosuppressive drugs used in the transplantation period are generally defined as
induction and maintenance therapy. The use of immunosuppressants, which are particularly …

Kidney transplantation is the optimal treatment for end-stage renal diseases. Although great
improvement has been achieved, immune tolerance is still the Holy Grail that every organ …

Establishing long-term allograft acceptance without the requirement for continuous
immunosuppression, a condition known as allograft tolerance, is a highly desirable …

Identifying transplant recipients in whom immunological tolerance is established or is
developing would allow an individually tailored approach to their posttransplantation …

Several transplant patients maintain stable kidney graft function in the absence of
immunosuppression. Here we compared the characteristics of their peripheral B cells to that …

Whereas a B cell–transcriptional profile has been recorded for operationally tolerant kidney
graft patients, the role that B cells have in this tolerance has not been reported. In this study …

Artificial intelligence (AI) refers to computer algorithms used to complete tasks that usually
require human intelligence. Typical examples include complex decision-making and-image …

Operationally tolerant patients (TOL) display a higher number of blood B cells and
transcriptional B cell signature. As they rarely develop an allo-immune response, they could …

The role of Foxp3+ regulatory T cells (Tregs) in operational tolerance remains elusive, as
initial results revealed an increased frequency of this subset in tolerant patients but no …

Obstacles to morbidity‐free long‐term survival after liver transplantation (LT) include
complications of immunosuppression (IS), recurrence of the original disease and …