Smiles rearrangement, an organic intramolecular nucleophilic aromatic substitution reaction,
provides a powerful access to the synthesis of a variety of heterocyclic compounds. In …

N, N′-(4, 4′-Sulfonylbis (4, 1-phenylene)) bis (2-cyanoacetamid) 2 was utilized as a key
intermediate for the synthesis of novel dihydropyridines 3, 4, 8, dihydroisoquinolines 5–7 …

The present article describes the synthesis of new 4 H-1, 4-benzothiazines via condensation
and oxidative cyclization of substituted 2-aminobenzenethiols with β-diketones/β-ketoesters …

This article deals with the study of the nitration of 4-chloro-3-nitrobenzoic acid. The substrate
is highly deactivated for SEAr reactions and therefore strict conditions are required …

Reaction of aryloxyacetic acid hydrazides 1a, b with α-haloketones such as hydrazonoyl
chlorides 2a, b; phenacyl bromides 6a, b; and 2-chloro-N-(1, 3-thiazol-2-yl) acetamide 10 …

A new series of eleven novel 1-(3-chloro-2-oxo-4-phenylazetidin-1yl)-3-(2-oxo-2-(10 H-
phenothiazin-10-yl) ethyl) urea derivatives were synthesized by cyclocondensation of …

The condensation reaction of 2-aminobenzenethiols and 3-aminopyrazinethiols with 2-
amino-6-fluoro-N-methylpyridinium triflate afforded thioether derivatives that were found to …

The current research article involves one pot synthesis of novel substituted 1-nitro-10 H-
phenothiazines via Smiles rearrangement. These substituted phenothiazines undergo …

In continuation of our work on synthesis of novel anticancer agents, a new series of
sulfonamides carrying a biologically active thiourea 3, 4, biphenylsulfones bearing thiourea …

Background: During the last years, condensed pyrimidine compounds have received much
attention because of their immense biological properties. These compounds have gained …