Multifunctional hybrid nanoparticles in diagnosis and therapy of breast cancer
Breast cancer is the most prevalent non-cutaneous malignancy in women, with greater than
a million new cases every year. In the last decennium, numerous diagnostic and treatment …
a million new cases every year. In the last decennium, numerous diagnostic and treatment …
[HTML][HTML] Hesperidin and its aglycone hesperetin in breast cancer therapy: A review of recent developments and future prospects
Breast cancer (BC) has high incidence and mortality rates, making it a major global health
issue. BC treatment has been challenging due to the presence of drug resistance and the …
issue. BC treatment has been challenging due to the presence of drug resistance and the …
Hydroxycitric acid reverses tamoxifen resistance through inhibition of ATP citrate lyase
Lipid metabolic reprogramming is involved in mediating tamoxifen (TAM) response in breast
cancer cells. Published microarray data indicated that ATP citrate lyase (ACLY) is …
cancer cells. Published microarray data indicated that ATP citrate lyase (ACLY) is …
Targeted degradation of transcription factors by TRAFTACs: transcription factor targeting chimeras
KTG Samarasinghe, S Jaime-Figueroa, M Burgess… - Cell chemical …, 2021 - cell.com
Many diseases, including cancer, stem from aberrant activation or overexpression of
oncoproteins that are associated with multiple signaling pathways. Although proteins with …
oncoproteins that are associated with multiple signaling pathways. Although proteins with …
Molecular mechanisms of endocrine resistance in estrogen-receptor-positive breast cancer
EB Belachew, DT Sewasew - Frontiers in endocrinology, 2021 - frontiersin.org
The estrogen receptor is a vital receptor for therapeutic targets in estrogen receptor-positive
breast cancer. The main strategy for the treatment of estrogen receptor-positive breast …
breast cancer. The main strategy for the treatment of estrogen receptor-positive breast …
The landscape of exosomal non-coding RNAs in breast cancer drug resistance, focusing on underlying molecular mechanisms
M Rezaee, F Mohammadi… - Frontiers in …, 2023 - frontiersin.org
Breast cancer (BC) is the most common malignancy among women worldwide. Like many
other cancers, BC therapy is challenging and sometimes frustrating. In spite of the various …
other cancers, BC therapy is challenging and sometimes frustrating. In spite of the various …
CBP/p300: critical co-activators for nuclear steroid hormone receptors and emerging therapeutic targets in prostate and breast cancers
Simple Summary The CREB-binding protein (CBP) and p300 are paralogous lysine
acetyltransferases that serve as critical co-activators for transcription factors involved in …
acetyltransferases that serve as critical co-activators for transcription factors involved in …
Adenylate kinase 4 modulates the resistance of breast cancer cells to tamoxifen through an m6A-based epitranscriptomic mechanism
N 6-methyladenosine (m 6 A) is the most abundant internal modification in mRNA and this
methylation constitutes an important regulatory mechanism for the stability and translational …
methylation constitutes an important regulatory mechanism for the stability and translational …
Estrogen alpha receptor antagonists for the treatment of breast cancer: a review
D Sharma, S Kumar, B Narasimhan - Chemistry Central Journal, 2018 - Springer
Background Cancer is at present one of the leading causes of death in the world. It accounts
for 13% of deaths occurred worldwide and is continuously rising, with an estimated million of …
for 13% of deaths occurred worldwide and is continuously rising, with an estimated million of …
Overview of solid lipid nanoparticles in breast cancer therapy
Lipid nanoparticles (LNPs), composed of ionized lipids, helper lipids, and cholesterol,
provide general therapeutic effects by facilitating intracellular transport and avoiding …
provide general therapeutic effects by facilitating intracellular transport and avoiding …