Covering: 1990 to 2015 The clerodane diterpenoids are a widespread class of secondary
metabolites and have been found in several hundreds of plant species from various families …

A frequent question when dealing with the search for gastroprotective compounds from
natural sources is how far or close are both the plant preparations and extract amounts from …

Ulcerative colitis is an inflammatory chronic disease that affects the mucosa and submucosa
of the colon and rectum. Several types of drugs are available such as aminosalicylates …

Byrsonima crassa Niedenzu (IK)(Malpighiaceae) is used in Brazilian folk medicine for the
treatment of diseases related mainly to gastric ulcers. In this study, we evaluated the …

Dehydroabietic acid derivatives have been reported to display antisecretory and antipepsin
effect in animal models. Some 19 dehydroabietic acid diterpenes were prepared and …

A new jatrophone derivative (6), jatrophone (3), jatropholone A (4) and jatropholone B (5),
acetyl aleuritolic acid (1), cyperenoic acid (2) and a monoterpene were isolated from the …

Ethnobotanical claims regarding Kigelia africana reported antiulcer properties as part of its
medicinal application. In this work, aqueous leaf extract from K. africana was investigated for …

Extensive use of certain drugs, changes in lifestyles and food habits, as well as stress factors
in modern human lives have led to an exponential increase in the incidence of gastric …

The resin from the tree Araucaria araucana (Araucariaceae) has been used since pre-
columbian times by the Mapuche amerindians to treat ulcers. The gastroprotective effect of …

The gastroprotective mechanism of the natural diterpene ferruginol was assessed in mice
and rats. The involvement of gastric prostaglandins (PGE2), reduced glutathione, nitric oxide …