[HTML][HTML] Toxoplasma gondii infection and toxoplasmosis in farm animals: Risk factors and economic impact

S Stelzer, W Basso, JB Silván, LM Ortega-Mora… - Food and waterborne …, 2019 - Elsevier
The protozoan parasite Toxoplasma gondii is a zoonotic parasite that can be transmitted
from animals to humans. Felids, including domestic cats, are definitive hosts that can shed …

Economic and public health importance of Toxoplasma gondii infections in sheep: 2009–2020

JP Dubey, FHA Murata, CK Cerqueira-Cézar… - Veterinary …, 2020 - Elsevier
Toxoplasma gondii infections are common in humans and animals worldwide. The present
review summarizes worldwide information on the prevalence of clinical and subclinical …

Unifying Virulence Evaluation in Toxoplasma gondii: A Timely Task

R Calero-Bernal, M Fernández-Escobar… - Frontiers in Cellular …, 2022 - frontiersin.org
Toxoplasma gondii, a major zoonotic pathogen, possess a significant genetic and
phenotypic diversity that have been proposed to be responsible for the variation in clinical …

An Early Treatment With BKI-1748 Exhibits Full Protection Against Abortion and Congenital Infection in Sheep Experimentally Infected With Toxoplasma gondii

R Sánchez-Sánchez, D Imhof, YP Hecker… - The Journal of …, 2024 - academic.oup.com
Congenital toxoplasmosis in humans and in other mammalian species, such as small
ruminants, is a well-known cause of abortion and fetal malformations. The calcium …

Isolation and genetic characterization of Toxoplasma gondii in Spanish sheep flocks

M Fernández-Escobar, R Calero-Bernal, J Benavides… - Parasites & vectors, 2020 - Springer
Background Toxoplasma gondii is a major cause of abortion in small ruminants and
presents a zoonotic risk when undercooked meat containing cysts is consumed. The aim of …

Toxoplasma gondii infection in slaughtered pigs and cattle in Poland: seroprevalence, molecular detection and characterization of parasites in meat

J Sroka, J Karamon, A Wójcik-Fatla, W Piotrowska… - Parasites & vectors, 2020 - Springer
Background Toxoplasma gondii infection may pose a severe medical problem especially in
a congenital form and as an acquired infection in immunocompromised persons. Raw and …

Differential affinity chromatography coupled to mass spectrometry: A suitable tool to identify common binding proteins of a broad-range antimicrobial peptide derived …

J Müller, G Boubaker, D Imhof, K Hänggeli… - Biomedicines, 2022 - mdpi.com
Leucinostatins are antimicrobial peptides with a broad range of activities against infectious
agents as well as mammalian cells. The leucinostatin-derivative peptide ZHAWOC_6027 …

[HTML][HTML] A comparative study of serological tests used in the diagnosis of Toxoplasma gondii infection in small ruminants evidenced the importance of cross-reactions …

NM López-Ureña, R Calero-Bernal… - Research in Veterinary …, 2023 - Elsevier
Toxoplasma gondii is a major foodborne zoonotic pathogen that can be transmitted through
the consumption of raw or undercooked meat of small ruminants, among others. Serology …

In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora …

D Imhof, N Anghel, P Winzer, V Balmer… - International Journal for …, 2021 - Elsevier
Bumped kinase inhibitors (BKIs) target the apicomplexan calcium-dependent protein kinase
1 (CDPK1). BKI-1748, a 5-aminopyrazole-4-carboxamide compound when added to …

Toxoplasma effectors that affect pregnancy outcome

D Arranz-Solís, D Mukhopadhyay, JJP Saeij - Trends in parasitology, 2021 - cell.com
As an immune-privileged organ, the placenta can tolerate the introduction of antigens
without inducing a strong inflammatory response that would lead to abortion. However, for …