Drosophila melanogaster spermatids undergo dramatic morphological changes as they
differentiate from small round cells approximately 12 μm in diameter into highly polarized …

BACKGROUND The precise movement of proteins and vesicles is an essential ability for all
eukaryotic cells. Nowhere is this more evident than during the remarkable transformation …

Myosin VI is thought to function as both a transporter and an anchor. While in vitro studies
suggest possible mechanisms for processive stepping, a biochemical basis for anchoring …

Unconventional myosins are a superfamily of actin-based motors implicated in diverse
cellular processes. In recent years, much progress has been made in describing their …

▪ Abstract Myosin motor proteins use the energy derived from ATP hydrolysis to move cargo
along actin tracks. Myosin VI, unlike almost all other myosins, moves toward the minus end …

Actin is found at the cortex of the cell where endocytosis occurs, but does it play a role in this
essential process? Recent studies on the unconventional myosin, myosin VI, an actin-based …

Myosin VI is involved in a wide variety of intracellular processes such as endocytosis,
secretion and cell migration. Unlike almost all other myosins so far studied, it moves towards …

In order to better understand the mechanism of sperm individualization during
spermatogenesis in Drosophila melanogaster, we have developed an in vitro culture system …

The recently solved structure of the myosin VI motor demonstrates that the unique insert at
the end of the motor is responsible for the reversal of the normal myosin directionality. A …

The myosin motor protein myosin VI plays an essential role in mammalian spermatogenesis,
however, the effects of myosin VI on male reproduction in Crustacea remain obscure. We …