Continuous flow separations in microfluidic devices

N Pamme - Lab on a Chip, 2007 - pubs.rsc.org
Biochemical sample mixtures are commonly separated in batch processes, such as filtration,
centrifugation, chromatography or electrophoresis. In recent years, however, many research …

Scaling and the design of miniaturized chemical-analysis systems

D Janasek, J Franzke, A Manz - Nature, 2006 - nature.com
Micrometre-scale analytical devices are more attractive than their macroscale counterparts
for various reasons. For example, they use smaller volumes of reagents and are therefore …

Micro total analysis systems. Latest advancements and trends

PS Dittrich, K Tachikawa, A Manz - Analytical chemistry, 2006 - ACS Publications
The area of micro total analysis systems (μTAS), also called “lab on a chip”, miniaturized or
microfluidic analysis systems, is a rapidly developing field. During the last several years, we …

Sample preparation

Y Chen, Z Guo, X Wang, C Qiu - Journal of Chromatography A, 2008 - Elsevier
A panorama of sample preparation methods has been composed from 481 references, with
a highlight of some promising methods fast developed during recent years and a somewhat …

Molecular sieving using nanofilters: past, present and future

J Han, J Fu, RB Schoch - Lab on a Chip, 2008 - pubs.rsc.org
Filtration of molecules by nanometer-sized structures is ubiquitous in our everyday life, but
our understanding of such molecular filtration processes is far less than desired. Until …

Micro free-flow electrophoresis: theory and applications

RT Turgeon, MT Bowser - Analytical and bioanalytical chemistry, 2009 - Springer
Free-flow electrophoresis (FFE) is a technique that performs an electrophoretic separation
on a continuous stream of analyte as it flows through a planar flow channel. The electric field …

Miniaturizing free‐flow electrophoresis–a critical review

D Kohlheyer, JCT Eijkel, A van den Berg… - …, 2008 - Wiley Online Library
Free‐flow electrophoresis (FFE) separation methods have been developed and investigated
for around 50 years and have been applied not only to many types of analytes for various …

3D printed micro free-flow electrophoresis device

SK Anciaux, M Geiger, MT Bowser - Analytical chemistry, 2016 - ACS Publications
The cost, time, and restrictions on creative flexibility associated with current fabrication
methods present significant challenges in the development and application of microfluidic …

Anodic bonding

KM Knowles, ATJ Van Helvoort - International materials reviews, 2006 - Taylor & Francis
Originally developed in the late 1960s, anodic bonding, also known as electrostatic bonding,
field-assisted bonding or Mallory bonding, has become one of the most important silicon …

Free-flow zone electrophoresis and isoelectric focusing using a microfabricated glass device with ion permeable membranes

D Kohlheyer, GAJ Besselink, S Schlautmann… - Lab on a Chip, 2006 - pubs.rsc.org
This paper describes a microfabricated free-flow electrophoresis device with integrated ion
permeable membranes. In order to obtain continuous lanes of separated components an …