Renin‐angiotensin aldosterone system inhibitors and COVID‐19: a systematic review and meta‐analysis revealing critical bias across a body of observational …

J Loader, FC Taylor, E Lampa… - Journal of the American …, 2022 - Am Heart Assoc
Background Renin‐angiotensin aldosterone system (RAAS) inhibitor—COVID‐19 studies,
observational in design, appear to use biased methods that can distort the interaction …

An umbrella review and meta‐analysis of renin–angiotensin system drugs use and COVID‐19 outcomes

A Kurdi, T Mueller, N Weir - European journal of clinical …, 2023 - Wiley Online Library
Background Despite the availability of extensive literature on the effect of angiotensin‐
converting enzyme inhibitors (ACEIs)/angiotensin‐receptor blockers (ARBs) on COVID‐19 …

Effects of renin–angiotensin system inhibitors on mortality and disease severity of COVID-19 patients: a meta-analysis of randomized controlled trials

J Yin, C Wang, X Song, X Li… - American Journal of …, 2022 - academic.oup.com
BACKGROUND There is controversy over the effects of angiotensin-converting enzyme
inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) on the prognosis in patients …

Randomized prospective open label study shows no impact on clinical outcome of adding losartan to hospitalized COVID-19 patients with mild hypoxemia

M Geriak, F Haddad, R Kullar, KL Greenwood… - Infectious diseases and …, 2021 - Springer
Introduction Despite considerable scientific debate, there have been no prospective clinical
studies on the effects of angiotensin II receptor blockers (ARBs) on the course of COVID-19 …

[HTML][HTML] Overreactive macrophages in SARS-CoV-2 infection: The effects of ACEI

D Felkle, K Zięba, K Kaleta, J Czaja, A Zyzdorf… - International …, 2023 - Elsevier
Among various factors influencing the course of SARS-CoV-2 infection in humans,
macrophage overactivation is considered the main cause of the cytokine storm that leads to …

[HTML][HTML] Potential use of renin-angiotensin-aldosterone system inhibitors to reduce COVID-19 severity

J Gonçalves, CD Santos, P Fresco… - Revista Portuguesa de …, 2023 - Elsevier
SARS-CoV-2 infection and its clinical manifestations (COVID-19) quickly evolved to a
pandemic and a global public health emergency. The limited effectivity of available …

Drugs in primary care that may alter COVID-19 risk and severity

B Luu, S Wijesinghe, T Kassem, J Lien, D Luu… - JAAPA, 2023 - journals.lww.com
This article describes drugs used in primary care that could alter patients' risk for and
severity of COVID-19. The risks and benefits of each drug class were differentiated …

An umbrella review and meta-analysis of the use of renin-angiotensin system drugs and COVID-19 outcomes: what do we know so far?

A Kurdi, N Weir, T Mueller - medRxiv, 2022 - medrxiv.org
Backgrounds Evidence from several meta-analyses are still controversial about the effects of
angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin-receptor blockers (ARBs) on …

Angiotensin II Receptor Blocking Drugs May Increase Severity of Coronavirus Disease 2019 Infection

R Cobos-Campos, C Bermudez-Ampudia… - American Journal of …, 2022 - journals.lww.com
9. Vallejos J, Zoni R, Bangher M, et al. Ivermectin to prevent hospitalizations in patients with
COVID-19 (IVERCOR-COVID19) a randomized, double-blind, placebo-controlled trial. BMC …

[PDF][PDF] OUTCOMES OF PATIENTS WITH HYPERTENSION TREATED WITH ANGIOTENSIN RECEPTOR BLOCKERS (ARBS) VS. ANGIOTENSIN-CONVERTING …

Y Vadlamannati, SB Sayana, TS Sai… - Int J Acad Med …, 2024 - academicmed.org
Background: Hypertension is a major risk factor for cardiovascular diseases. Angiotensin
receptor blockers (ARBs) and angiotensin-converting enzyme inhibitors (ACEIs) are …