Ketone bodies: from enemy to friend and guardian angel

H Kolb, K Kempf, M Röhling, M Lenzen-Schulte… - BMC medicine, 2021 - Springer
During starvation, fasting, or a diet containing little digestible carbohydrates, the circulating
insulin levels are decreased. This promotes lipolysis, and the breakdown of fat becomes the …

Dietary regulation in health and disease

Q Wu, ZJ Gao, X Yu, P Wang - Signal Transduction and Targeted …, 2022 - nature.com
Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

[HTML][HTML] Nutrition therapy for adults with diabetes or prediabetes: a consensus report

AB Evert, M Dennison, CD Gardner, WT Garvey… - Diabetes …, 2019 - ncbi.nlm.nih.gov
This Consensus Report is intended to provide clinical professionals with evidencebased
guidance about individualizing nutrition therapy for adults with diabetes or prediabetes …

Therapeutic Potential of Ketone Bodies for Patients With Cardiovascular Disease: JACC State-of-the-Art Review

SR Yurista, CR Chong, JJ Badimon, DP Kelly… - Journal of the American …, 2021 - jacc.org
Metabolic perturbations underlie a variety of cardiovascular disease states; yet, metabolic
interventions to prevent or treat these disorders are sparse. Ketones carry a negative clinical …

Lifestyle factors and high-risk atherosclerosis: Pathways and mechanisms beyond traditional risk factors

K Lechner, C von Schacky… - European journal of …, 2020 - journals.sagepub.com
Despite major efforts to reduce atherosclerotic cardiovascular disease (ASCVD) burden with
conventional risk factor control, significant residual risk remains. Recent evidence on non …

Long-term effects of a novel continuous remote care intervention including nutritional ketosis for the management of type 2 diabetes: a 2-year non-randomized clinical …

SJ Athinarayanan, RN Adams, SJ Hallberg… - Frontiers in …, 2019 - frontiersin.org
Purpose: Studies on long-term sustainability of low-carbohydrate approaches to treat
diabetes are limited. We previously reported the effectiveness of a novel digitally-monitored …

The ketogenic diet: Pros and cons

B O'Neill, P Raggi - Atherosclerosis, 2020 - Elsevier
Diets have been at the center of animated debates for decades and many claims have been
made in one direction or the other by supporters of opposite camps, often with limited …

3-hydroxybutyrate as a metabolite and a signal molecule regulating processes of living organisms

J Mierziak, M Burgberger, W Wojtasik - Biomolecules, 2021 - mdpi.com
3-hydroxybutyrate (3-HB) as a very important metabolite occurs in animals, bacteria and
plants. It is well known that in animals, 3-HB is formed as a product of the normal metabolism …

Dietary fat: from foe to friend?

DS Ludwig, WC Willett, JS Volek, ML Neuhouser - Science, 2018 - science.org
For decades, dietary advice was based on the premise that high intakes of fat cause obesity,
diabetes, heart disease, and possibly cancer. Recently, evidence for the adverse metabolic …

[HTML][HTML] Low-carb and ketogenic diets in type 1 and type 2 diabetes

AM Bolla, A Caretto, A Laurenzi, M Scavini, L Piemonti - Nutrients, 2019 - mdpi.com
Low-carb and ketogenic diets are popular among clinicians and patients, but the
appropriateness of reducing carbohydrates intake in obese patients and in patients with …