Hypoxia is a common feature of solid tumors, and develops because of the rapid growth of
the tumor that outstrips the oxygen supply, and impaired blood flow due to the formation of …

Experimental work of the last two decades has revealed the general steps of the wound
healing process. This complex network has been organized in three sequential and …

Cancer progression often benefits from the selective conditions present in the tumour
microenvironment, such as the presence of cancer-associated fibroblasts (CAFs) …

Pulmonary hypertension (PH) is characterized by pulmonary artery remodeling that can
subsequently culminate in right heart failure and premature death. Emerging evidence …

Acute kidney injury (AKI) is a major kidney disease characterized by an abrupt loss of renal
function. Accumulating evidence indicates that incomplete or maladaptive repair after AKI …

Probiotic lactic acid bacteria (LAB) are a particular group of gram-positive bacteria that are
usually involved in natural ferments and widely used in food manufacture industry. Most of …

Low oxygen tension (hypoxia) is a hallmark of cancer that influences cancer cell function,
but is also an important component of the tumour microenvironment as it alters the …

In contrast to the general belief, endothelial cell (EC) metabolism has recently been
identified as a driver rather than a bystander effect of angiogenesis in health and disease …

Infection, cancer and cardiovascular diseases are the major causes for morbidity and
mortality in the United States according to the Center for Disease Control. The underlying …

Humans have adapted to the chronic hypoxia of high altitude in several locations, and
recent genome-wide studies have indicated a genetic basis. In some populations, genetic …