ES Gargus, HB Rogers, KE McKinnon… - Nature biomedical …, 2020 - nature.com
Engineered male and female biomimetic reproductive tissues are being developed as autonomous in vitro units or as integrated multi-organ in vitro systems to support germ cell …
Extracellular matrix (ECM)-based bioinks has attracted much attention in recent years for 3D printing of native-like tissue constructs. Due to organ unavailability, human placental ECM …
Y Huang, Z Huang, Z Tang, Y Chen… - Frontiers in Cell and …, 2021 - frontiersin.org
Traditional cell lines and xenograft models have been widely recognized and used in research. As a new research model, organoids have made significant progress and …
This research presents a novel testis-on-a-chip (ToC) platform. Testicular cells are enzymatically isolated from the seminiferous tubules of sexually immature mice, seeded in a …
Testicular scaffolds may be an option for fertility preservation. The aim was to develop various procedures for the decellularization of testicular tissue and to design a bio-ink to …
X Liu, K Wu, L Gao, L Wang, X Shi - Bioactive Materials, 2022 - Elsevier
Human reproductive organs are of vital importance to the life of an individual and the reproduction of human populations. So far, traditional methods have a limited effect in …
Since autologous stem cell transplantation is prone to cancer recurrence, in vitro sperm production is regarded a safer approach to fertility preservation. In this study, the …
G Richer, Y Baert, E Goossens - Andrology, 2020 - Wiley Online Library
Background The testicular organoid concept has recently been introduced in tissue engineering to refer to testicular cell organizations modeling testicular architecture and …
The loss of germ cells and spermatogenic failure in non-obstructive azoospermia are believed to be the main causes of male infertility. Laboratory studies have used in vitro …