Quantitative magnetic resonance imaging (qMRI) goes beyond conventional MRI, which
aims primarily at local image contrast. It provides specific physical parameters related to the …

This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …

Neuroscience and clinical researchers are increasingly interested in quantitative magnetic
resonance imaging (qMRI) due to its sensitivity to micro-structural properties of brain tissue …

Pathophysiological changes in the spinal cord white and grey matter resulting from injury
can be observed with MRI techniques. These techniques provide sensitive markers of …

Abstract Properties of human brain tissue change across the lifespan. Here we model these
changes in the living human brain by combining quantitative magnetic resonance imaging …

The myelin g-ratio, defined as the ratio between the inner and the outer diameter of the
myelin sheath, is a fundamental property of white matter that can be computed from a simple …

The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

The image contrast in magnetic resonance imaging (MRI) is highly sensitive to several
mechanisms that are modulated by the properties of the tissue environment. The degree and …

Recent studies have shown that there is a direct link between the orientation of the nerve
fibers in white matter (WM) and the contrast observed in magnitude and phase images …

White matter tissue properties are highly correlated with reading proficiency; we would like
to have a model that relates the dynamics of an individual's white matter development to …