Oxidative stress (OS) is mediated by reactive oxygen species (ROS), which in
cardiovascular and other disease states, damage DNA, lipids, proteins, other cellular and …

Abstract LOX‐1 (lectin‐like oxidized low‐density lipoprotein receptor‐1; also known as
OLR1) is the dominant receptor that recognizes and internalizes oxidized low‐density …

Chronic obstructive pulmonary disease (COPD) is an incurable global health burden and is
characterised by progressive airflow limitation and loss of lung function. In addition to the …

Excessive levels of reactive oxygen species (ROS) and increased expression of NADPH
oxidases (Nox) have been proposed to contribute to pulmonary artery hypertension (PAH) …

Pulmonary hypertension (PH) is defined by a mean pulmonary arterial pressure over 25
mmHg at rest and is diagnosed by right heart catheterization. Among the different groups of …

High-altitude exposure results in hypobaric hypoxia, which affects organisms by activating
several mechanisms at the physiological, cellular, and molecular levels and triggering the …

Several epidemiological studies have clearly shown the high co-morbidity between
depression and Cardiovascular Diseases (CVD). Different studies have been conducted to …

Pulmonary hypertension (PH) is a multi-etiological condition with a similar hemodynamic
clinical sign and end result of right heart failure. Although its causes vary, a similar link …

Rationale: Progression of pulmonary arterial hypertension (PAH) is associated with
pathological remodeling of the pulmonary vasculature and the right ventricle (RV). Oxidative …

Pulmonary hypertension (PH) is a progressive disease characterized by elevated artery
pressures and pulmonary vascular resistance. Underlying mechanisms comprise …