The safety of metformin use for patients with type 2 diabetes mellitus (T2DM) and advanced
kidney disease is controversial, and more recent guidelines have suggested that metformin …

Metformin has been associated with lactic acidosis. Lactate levels are not commonly tested
in clinical practice, and it is unclear to what extent metformin would typically increase lactate …

Background Diabetes patients presenting with ST-segment elevation myocardial infarction
(STEMI) scheduled for primary percutaneous coronary intervention (PCI) have an increased …

Objectives Substantial inconsistencies exist in current guidelines regarding
recommendations of metformin usage with the administration of a contrast medium. We …

This paper demonstrated that a novel enteric osmotic pump capsule (EOPC) could
effectively deliver metformin hydrochloride (MH) into the small intestine and keep releasing …

Objectives The current guidelines contain substantial inconsistency regarding the use of
metformin concomitantly with contrast media. The objective of this study is to appraise the …

This study determined if the use of metformin affected the prognostic value of
hyperlactatemia in predicting 28-day mortality among patients with sepsis and bacteremia …

A growing body of evidence demonstrates obesity‐induced insulin resistance is associated
with the development of metabolic diseases. This study was designed to investigate ethyl …

Objective: The objective of this study was to investigate the correlation between metformin
exposure and the incidence of lactic acidosis in critically ill patients. Methods: The patients …

2. Method This is a retrospective cross-sectional study that was conducted at Dokuz Eylul
University Department of Emergency Medicine, which accepts approximately 135,000 …