Azide‐Modified Nucleosides as Versatile Tools for Bioorthogonal Labeling and Functionalization

F Müggenburg, S Müller - The Chemical Record, 2022 - Wiley Online Library
Azide‐modified nucleosides are important building blocks for RNA and DNA
functionalization by click chemistry based on azide‐alkyne cycloaddition. This has put …

Regiodivergent and stereoselective hydroxyazidation of alkenes by biocatalytic cascades

JF Wu, NW Wan, YN Li, QP Wang, BD Cui, WY Han… - Iscience, 2021 - cell.com
Asymmetric functionalization of alkenes allows the direct synthesis of a wide range of chiral
compounds. Vicinal hydroxyazidation of alkenes provides a desirable path to 1, 2 …

Azido Functionalized Nucleosides Linked to Controlled Pore Glass as Suitable Starting Materials for Oligonucleotide Synthesis by the Phosphoramidite Approach

F Müggenburg, A Biallas, M Debiais… - European Journal of …, 2021 - Wiley Online Library
It has long been debated whether easily reducible azide groups can withstand the
conditions of oligonucleotide synthesis by phosphoramidite chemistry. We have synthesized …

Advanced catalyst-free pseudo-six-component synthesis of tetrahydrodipyrazolopyridines in water by using ammonium carbonate as an ecofriendly source of nitrogen

F Tamaddon, A Khorram - Synlett, 2020 - thieme-connect.com
This work describes an improved environmentally friendly method for the synthesis of
tetrahydrodipyrazolopyridines (THDPPs) in water through a catalyst-free pseudo-six …

Multigram‐scale enzymatic kinetic resolution of trans‐2‐azidocyclohexyl acetate and chiral reversed‐phase HPLC analysis of trans‐2‐azidocyclohexanol

P Hebda, L Wiśniowska, PW Szafrański, M Cegła - Chirality, 2022 - Wiley Online Library
Lipase‐catalyzed hydrolytic kinetic resolution is a method of obtaining optically pure chiral
alcohols and amines, which requires additional tools for determining enantiomerical purity …

Synthesis and properties of methanesulfonyl derivatives of diethyl esters of 5-(hydroxyalkylamino)-1, 3-oxazol-4-yl-phosphonic acids

OV Golovchenko, MY Brusnakov… - … , Sulfur, and Silicon …, 2024 - Taylor & Francis
Abstract A number of {[4-(diethoxyphosphoryl)-2-R-1, 3-oxazol-5-yl] amino} alkyl
methanesulfonates were synthesized and the peculiarities of their reaction with triethylamine …

Синтез нової гетероциклічної системи [1, 3] оксазоло [4, 5-c][1, 5, 2] оксазафосфепіну

МЮ Бруснаков, ЮО Шишацька… - Доповіді НАН …, 2022 - dspace.nbuv.gov.ua
Досліджено властивості діетилових естерів 2-арил-1, 3-оксазол-4-ілфосфонових
кислот, що містять (2-гідроксіетил) аміногрупу в положенні 5 оксазольного циклу …

[PDF][PDF] Synthese modifizierter Nukleosidanaloga als wichtige Werkzeuge zur Generierung funktionaler Oligonukleotide

FA Müggenburg - 2023 - epub.ub.uni-greifswald.de
Die Dissertation beschreibt die Synthese verschiedener Nukleosidanaloga mit den
notwendigen Modifizierungen und Funktionalitäten für einen Einsatz in der Phosphoramidit …