[HTML][HTML] Inhalable neutralizing antibodies–promising approach to combating respiratory viral infections
Monoclonal antibodies represent an exciting class of therapeutics against respiratory viral
infections. Notwithstanding their specificity and affinity, the conventional parenteral …
infections. Notwithstanding their specificity and affinity, the conventional parenteral …
Characterizing regional drug delivery within the nasal airways
Introduction The nose has been receiving increased attention as a route for drug delivery. As
the site of deposition constitutes the first point of contact of the body with the drug …
the site of deposition constitutes the first point of contact of the body with the drug …
Synthesis of the first remdesivir cocrystal: design, characterization, and therapeutic potential for pulmonary delivery
While cocrystal engineering is an emerging formulation strategy to overcome drug delivery
challenges, its therapeutic potential in non-oral applications remains not thoroughly …
challenges, its therapeutic potential in non-oral applications remains not thoroughly …
Intranasal delivery of thin-film freeze-dried monoclonal antibodies using a powder nasal spray system
Monoclonal antibodies (mAbs) administered intranasally as dry powders can be potentially
applied for the treatment or pre-exposure prevention of viral infections in the upper …
applied for the treatment or pre-exposure prevention of viral infections in the upper …
Neutralisation of SARS-CoV-2 by monoclonal antibody through dual targeting powder formulation
Neutralising monoclonal antibody (mAb) is an important weapon in our arsenal for
combating respiratory viral infections. However, the effectiveness of neutralising mAb has …
combating respiratory viral infections. However, the effectiveness of neutralising mAb has …
Development of favipiravir dry powders for intranasal delivery: An integrated cocrystal and particle engineering approach via spray freeze drying
The therapeutic potential of pharmaceutical cocrystals in intranasal applications remains
largely unexplored despite progressive advancements in cocrystal research. We present the …
largely unexplored despite progressive advancements in cocrystal research. We present the …
Feasibility of intranasal delivery of thin-film freeze-dried monoclonal antibodies
YS Yu, H Xu, K AboulFotouh, G Williams, J Suman… - bioRxiv, 2023 - biorxiv.org
Monoclonal antibodies (mAbs) administered intranasally as dry powders can be potentially
applied for the treatment or pre-exposure prevention of viral infections in the upper …
applied for the treatment or pre-exposure prevention of viral infections in the upper …