Chalcones (1, 3-diaryl-2-propen-1-ones) are precursors for flavonoids and isoflavonoids,
which are common simple chemical scaffolds found in many naturally occurring compounds …

Cancer is the second leading cause of death worldwide, and it results in around 9 million
deaths annually. The anticancer agents play an intriguing role in the treatment of cancers …

Coumarins are fused benzene and pyrone ring systems which prompt biological
investigation to assess their potential therapeutic significance. It possesses immeasurable …

Coumarins are found in higher plants like Rutaceae and Umbelliferae and essential oils of
cinnamon bark, cassia leaf, and lavender oil. Coumarin compounds show different …

The continuous emergency of drug‐resistant cancers and the low specificity of anticancer
agents have been the major challenges in the control and treatment of cancer, making an …

Cancer is a multifactorial disease that requires treatments able to target multiple intracellular
components and signaling pathways. The natural compound, curcumin, was already …

Rheumatoid arthritis (RA) is a systemic chronic inflammatory disease associated with a
potential imbalance between the growth and death of rheumatoid arthritis fibroblast-like …

Naturally and synthetically derived hybrid molecules are an attractive source for therapeutic
agent development due to their dual or multiple modes of action and other advantages …

Coumarin class of organic compounds consists of 1, 2-benzopyrone ring system as a basic
parent scaffold. These benzopyrones are subdivided into alpha-benzopyrones and …

Cancer is an inevitable matter of concern in the medicinal chemistry era. Chalcone is the
well exploited scaffold in the anticancer domain. The molecular mechanism of chalcone at …