Bilirubin nanomedicines for the treatment of reactive oxygen species (ROS)-mediated diseases
Z Chen, CT Vong, C Gao, S Chen, X Wu… - Molecular …, 2020 - ACS Publications
Reactive oxygen species (ROS) are chemically reactive species that are produced in
cellular aerobic metabolism. They mainly include superoxide anion, hydrogen peroxide …
cellular aerobic metabolism. They mainly include superoxide anion, hydrogen peroxide …
Iron metabolism in erythroid cells and patients with congenital sideroblastic anemia
K Furuyama, K Kaneko - International Journal of Hematology, 2018 - Springer
Sideroblastic anemias are anemic disorders characterized by the presence of ring
sideroblasts in a patient's bone marrow. These disorders are typically divided into two types …
sideroblasts in a patient's bone marrow. These disorders are typically divided into two types …
Potential role of heme metabolism in the inducible expression of heme oxygenase-1
T Takeda, M Sasai, Y Adachi, K Ohnishi… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background The degradation of heme significantly contributes to cytoprotective effects
against oxidative stress and inflammation. The enzyme heme oxygenase-1 (HO-1), involved …
against oxidative stress and inflammation. The enzyme heme oxygenase-1 (HO-1), involved …
Upregulation of matrix metalloproteinase triggers transdifferentiation of retinal pigmented epithelial cells in Xenopus laevis: A Link between inflammatory response …
H Naitoh, Y Suganuma, Y Ueda, T Sato… - Developmental …, 2017 - Wiley Online Library
In adult Xenopus eyes, when the whole retina is removed, retinal pigmented epithelial (RPE)
cells become activated to be retinal stem cells and regenerate the whole retina. In the …
cells become activated to be retinal stem cells and regenerate the whole retina. In the …
The novel heme-dependent inducible protein, SRRD regulates heme biosynthesis and circadian rhythms
Y Adachi, M Umeda, A Kawazoe, T Sato… - Archives of biochemistry …, 2017 - Elsevier
Heme plays a role in the regulation of the expression of genes related to circadian rhythms
and heme metabolism. In order to identify new heme-regulated proteins, an RNA sequence …
and heme metabolism. In order to identify new heme-regulated proteins, an RNA sequence …
Development of Bilirubin-Based Drug Delivery Systems for the Treatment of Inflammatory Bowel Disease
Z Chen - 2023 - search.proquest.com
Ulcerative colitis (UC) is a high incidence disease worldwide and clinically presented as
relapsing morbidity and incurable inflammation of the colon. With the development of …
relapsing morbidity and incurable inflammation of the colon. With the development of …
Chemical and thyroid hormone profile of the bone marrow interstitial fluid in hematologic disorders and patients without primary hematologic disorders
E Krashin, M Ellis, K Cohen, M Viner… - Hematological …, 2018 - Wiley Online Library
Bone marrow interstitial fluid (BMIF) has not been well characterized. BMIF was isolated
from 60 patients including plasma cell dyscrasias (PCD, n= 33), other primary hematologic …
from 60 patients including plasma cell dyscrasias (PCD, n= 33), other primary hematologic …