[HTML][HTML] APOBECs and virus restriction
RS Harris, JP Dudley - Virology, 2015 - Elsevier
The APOBEC family of single-stranded DNA cytosine deaminases comprises a formidable
arm of the vertebrate innate immune system. Pre-vertebrates express a single APOBEC …
arm of the vertebrate innate immune system. Pre-vertebrates express a single APOBEC …
HIV-1 Vif, APOBEC, and intrinsic immunity
R Goila-Gaur, K Strebel - Retrovirology, 2008 - Springer
Members of the APOBEC family of cellular cytidine deaminases represent a recently
identified group of proteins that provide immunity to infection by retroviruses and protect the …
identified group of proteins that provide immunity to infection by retroviruses and protect the …
[HTML][HTML] Complementary function of the two catalytic domains of APOBEC3G
F Navarro, B Bollman, H Chen, R König, Q Yu, K Chiles… - Virology, 2005 - Elsevier
The HIV-1 viral accessory protein Vif prevents the encapsidation of the antiviral cellular
cytidine deaminases APOBEC3F and APOBEC3G by inducing their proteasomal …
cytidine deaminases APOBEC3F and APOBEC3G by inducing their proteasomal …
Identification of APOBEC3DE as another antiretroviral factor from the human APOBEC family
Y Dang, X Wang, WJ Esselman, YH Zheng - Journal of virology, 2006 - Am Soc Microbiol
ABSTRACT A tandem arrayed gene cluster encoding seven cytidine deaminase genes is
present on human chromosome 22. These are APOBEC3A, APOBEC3B, APOBEC3C …
present on human chromosome 22. These are APOBEC3A, APOBEC3B, APOBEC3C …
Cytidine deaminases APOBEC3G and APOBEC3F interact with human immunodeficiency virus type 1 integrase and inhibit proviral DNA formation
K Luo, T Wang, B Liu, C Tian, Z Xiao, J Kappes… - Journal of …, 2007 - Am Soc Microbiol
ABSTRACT APOBEC3G (A3G) is a single-stranded DNA cytidine deaminase that targets
retroviral minus-strand DNA and has potent antiviral activity against diverse retroviruses …
retroviral minus-strand DNA and has potent antiviral activity against diverse retroviruses …
Suppression of APOBEC3-mediated restriction of HIV-1 by Vif
The APOBEC3 restriction factors are a family of deoxycytidine deaminases that are able to
suppress replication of viruses with a single-stranded DNA intermediate by inducing …
suppress replication of viruses with a single-stranded DNA intermediate by inducing …
Exosomes packaging APOBEC3G confer human immunodeficiency virus resistance to recipient cells
AK Khatua, HE Taylor, JEK Hildreth, W Popik - Journal of virology, 2009 - Am Soc Microbiol
The human cytidine deaminase APOBEC3G (A3G) is a part of a cellular defense system
against human immunodeficiency virus type 1 (HIV-1) and other retroviruses. Antiretroviral …
against human immunodeficiency virus type 1 (HIV-1) and other retroviruses. Antiretroviral …
The retroviral hypermutation specificity of APOBEC3F and APOBEC3G is governed by the C-terminal DNA cytosine deaminase domain
G Haché, MT Liddament, RS Harris - Journal of Biological Chemistry, 2005 - ASBMB
The human proteins APOBEC3F and APOBEC3G restrict retroviral infection by deaminating
cytosine residues in the first cDNA strand of a replicating virus. These proteins have two …
cytosine residues in the first cDNA strand of a replicating virus. These proteins have two …
Host restriction factors blocking retroviral replication
D Wolf, SP Goff - Annual review of genetics, 2008 - annualreviews.org
Retroviruses are highly successful intracellular parasites, and as such they are found in
nearly all branches of life. Some are relatively benign, but many are highly pathogenic and …
nearly all branches of life. Some are relatively benign, but many are highly pathogenic and …
Mutational comparison of the single-domained APOBEC3C and double-domained APOBEC3F/G anti-retroviral cytidine deaminases provides insight into their DNA …
Abstract Human APOBEC3F and APOBEC3G are double-domained deaminases that can
catalyze dC→ dU deamination in HIV-1 and MLV retroviral DNA replication intermediates …
catalyze dC→ dU deamination in HIV-1 and MLV retroviral DNA replication intermediates …