L Guerra, E Dellambra, S Brescia… - Current drug …, 2010 - ingentaconnect.com
Vitiligo is a multifactorial disorder characterized by the appearance of white maculae that may spread over the entire body skin. Depigmentation arises from the loss of functioning …
Background Vitiligo is an autoimmune disease of the skin with limited treatment options; there is an urgent need to identify and validate biomarkers of disease activity to support …
Systemic as well as localized skin diseases modify the molecular composition of human skin. Changes in skin chemistry have been observed in diseases such as cancer, psoriasis …
Autoimmune skin diseases are complex processes in which autoreactive cells must navigate through the skin tissue to find their targets. Regulatory T cells in the skin help to mitigate …
H Shi, B Lin, Y Huang, J Wu, H Zhang, C Lin… - IUBMB …, 2016 - Wiley Online Library
Vitiligo is a depigmentation disorder characterized by loss of functional melanocytes of the skin epidermis. The pathogenesis of vitiligo remains elusive. The purpose of this study is to …
H Seif El Nasr, OG Shaker, MMT Fawzi… - Journal of the …, 2013 - Wiley Online Library
Background In healthy skin, there is a molecular microenvironment that favours the survival of melanocytes and regulates their function. Keratinocytes synthesize and secrete several …
P Wang, Y Li, H Nie, X Zhang, Q Shao, X Hou… - Journal of …, 2016 - Elsevier
Background Vitiligo is a common acquired depigmentation skin disease characterized by loss or dysfunction of melanocytes within the skin lesion, but its pathologenesis is far from …
Vitiligo is a manageable disease. However, current vitiligo treatments can be considered suboptimal as they do not guarantee high efficacy and cannot be standardized for most …