Amyloidogenesis via interfacial shear in a containerless biochemical reactor aboard the International Space Station

P McMackin, J Adam, S Griffin, A Hirsa - npj Microgravity, 2022 - nature.com
Fluid interfaces significantly influence the dynamics of protein solutions, effects that can be
isolated by performing experiments in microgravity, greatly reducing the amount of solid …

Single-camera PTV within interfacially sheared drops in microgravity

PM McMackin, JA Adam, FP Riley, AH Hirsa - Experiments in Fluids, 2023 - Springer
Abstract Development of experimental methods for in situ particle tracking velocimetry (PTV)
is fundamental for allowing measurement of moving systems non-tailored for velocimetry …

Coupling vortical bulk flows to the air–water interface: from putting oil on troubled waters to surfactants on protein solutions

AH Hirsa, JM Lopez - Fluids, 2021 - mdpi.com
The air–water interface in flowing systems remains a challenge to model, even in cases
where the interface is essentially flat. This is because even though each side is governed by …

[HTML][HTML] Flow in a ring-sheared drop: Drop deformation

FP Riley, PM McMackin, JM Lopez, AH Hirsa - Physics of Fluids, 2021 - pubs.aip.org
The ring-sheared drop is a containerless system where shear is imparted by two contact
rings, one rotating and the other stationary. In microgravity, aqueous drops can be studied in …

Simulated microgravity in the ring-sheared drop

PM McMackin, SR Griffin, FP Riley, S Gulati… - npj …, 2020 - nature.com
The ring-sheared drop is a module for the International Space Station to study sheared fluid
interfaces and their influence on amyloid fibril formation. A 2.54-cm diameter drop is …

Amyloidogenesis via interfacial shear in a containerless biochemical reactor aboard the International Space Station

A Hirsa, P McMackin, J Adam, S Griffin - 2022 - researchsquare.com
Fluid interfaces significantly influence the dynamics of protein solutions, effects that can be
isolated by performing experiments in microgravity, greatly reducing the amount of solid …