Nucleic acid tests for clinical translation

M Li, F Yin, L Song, X Mao, F Li, C Fan, X Zuo… - Chemical …, 2021 - ACS Publications
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Fluorescence polarization-based bioassays: new horizons

OD Hendrickson, NA Taranova, AV Zherdev… - Sensors, 2020 - mdpi.com
Fluorescence polarization holds considerable promise for bioanalytical systems because it
allows the detection of selective interactions in real time and a choice of fluorophores, the …

Mapping the gaps in chemical analysis for the characterisation of aptamer-target interactions

E Daems, G Moro, R Campos, K De Wael - TrAC Trends in Analytical …, 2021 - Elsevier
Aptamers are promising biorecognition elements with a wide applicability from therapeutics
to biosensing. However, to successfully use these biomolecules, a complete …

Fluorescence polarization assays for chemical contaminants in food and environmental analyses

H Zhang, S Yang, K De Ruyck, NV Beloglazova… - TrAC Trends in …, 2019 - Elsevier
Fluorescence polarization (FP) assays play an important role in the detection of chemical
contaminants in food and environmental due to a number of key advantages since last …

An enzyme-free DNA circuit-assisted graphene oxide enhanced fluorescence anisotropy assay for microRNA detection with improved sensitivity and selectivity

SJ Zhen, X Xiao, CH Li, CZ Huang - Analytical chemistry, 2017 - ACS Publications
Graphene oxide (GO) has been proven as an outstanding fluorescence anisotropy (FA)
amplifier. Yet the traditional GO amplified FA assays lack high sensitivity because of the 1: 1 …

Graphene signal amplification for sensitive and real-time fluorescence anisotropy detection of small molecules

J Liu, C Wang, Y Jiang, Y Hu, J Li, S Yang, Y Li… - Analytical …, 2013 - ACS Publications
Fluorescence anisotropy (FA) is a reliable, sensitive, and robust assay approach for
determination of many biological targets. However, it is generally not applicable for the …

Photoelectrochemical lab-on-paper device based on an integrated paper supercapacitor and internal light source

L Ge, P Wang, S Ge, N Li, J Yu, M Yan… - Analytical …, 2013 - ACS Publications
In this work, a photoelectrochemical (PEC) method was introduced into a microfluidic paper-
based analytical device (μ-PAD), and thus, a truly low-cost, simple, portable, and disposable …

Aptamer-based fluorescence polarization assay for separation-free exosome quantification

Z Zhang, C Tang, L Zhao, L Xu, W Zhou, Z Dong… - Nanoscale, 2019 - pubs.rsc.org
Tumor-derived exosomes have emerged as promising cancer biomarkers and attracted
increasing interest in non-invasive cancer diagnosis and treatment monitoring. However, the …

Rapid detection of tear lactoferrin for diagnosis of dry eyes by using fluorescence polarization-based aptasensor

Y Zhang, P Yan, H Tang, J Zhang - Scientific Reports, 2023 - nature.com
Differentiating dry eye disease (DED) from allergic or viral conjunctivitis rapidly and
accurately is important to ensure prompt diagnosis and treatment. Tear lactoferrin (LF), a …

Self-assembled DNA nanocentipede as multivalent drug carrier for targeted delivery

W Li, X Yang, L He, K Wang, Q Wang… - … applied materials & …, 2016 - ACS Publications
An idea drug carrier, with good binding affinity, selectivity, drug payload capacity, and
cellular internalized capability, will greatly improve the efficiency of target delivery. Herein a …