Chronic diseases, inflammation, and spices: how are they linked?

AB Kunnumakkara, BL Sailo, K Banik, C Harsha… - Journal of translational …, 2018 - Springer
Extensive research within the last several decades has revealed that the major risk factors
for most chronic diseases are infections, obesity, alcohol, tobacco, radiation, environmental …

Targeting obesity with plant-derived pancreatic lipase inhibitors: A comprehensive review

L Rajan, D Palaniswamy, SK Mohankumar - Pharmacological research, 2020 - Elsevier
The prevalence of obesity is alarmingly increasing in the last few decades and leading to
many serious public health concerns worldwide. The dysregulated lipid homeostasis due to …

Crocin: A fighter against inflammation and pain

M Hashemzaei, C Mamoulakis, K Tsarouhas… - Food and Chemical …, 2020 - Elsevier
Crocin, a water-soluble carotenoid, is known as a pharmacologically active compound,
particularly for its potent anti-oxidant activity. The present work provides a comprehensive …

The effect of ellagic acid on the metabolic syndrome: A review article

K Naraki, MG Rahbardar, BO Ajiboye, H Hosseinzadeh - Heliyon, 2023 - cell.com
Objective (s): Metabolic syndrome is a collection of metabolic abnormalities that includes
hyperglycemia, dyslipidemia, hypertension, and obesity. Ellagic acid is found in various …

[HTML][HTML] Therapeutic application and toxicity associated with Crocus sativus (saffron) and its phytochemicals

AK Wani, J Singh, S Shukla - Pharmacological Research-Modern …, 2022 - Elsevier
Saffron, a Crocus sativus L. derivative, has been recognized for its medical benefits since
ancient times. Besides being an active flavoring and coloring agent in several food items …

Effects of saffron supplementation on inflammation and metabolic responses in type 2 diabetic patients: A randomized, double-blind, placebo-controlled trial

F Ebrahimi, A Sahebkar, N Aryaeian… - … syndrome and obesity …, 2019 - Taylor & Francis
Background Type 2 diabetes (T2D) is accompanied by elevated inflammation, oxidative
stress, hyperlipidemia and hyperglycemia which all contribute to cardiovascular disease …

Crocins: A comprehensive review of structural characteristics, pharmacokinetics and therapeutic effects

Y Song, Y Wang, Y Zheng, T Liu, C Zhang - Fitoterapia, 2021 - Elsevier
Crocins, as a kind of water-soluble carotenoid pigment, are a series of ester compounds
formed from crocetin and gentibiose or glucose, and mainly distributed among Crocus …

Antidiabetic potential of saffron and its active constituents

H Yaribeygi, V Zare, AE Butler… - Journal of cellular …, 2019 - Wiley Online Library
The prevalence of diabetes mellitus is growing rapidly worldwide. This metabolic disorder
affects many physiological pathways and is a key underlying cause of a multitude of …

A comparative study of the role of crocin and sitagliptin in attenuation of STZ-induced diabetes mellitus and the associated inflammatory and apoptotic changes in …

MM Samaha, E Said, HA Salem - Environmental Toxicology and …, 2019 - Elsevier
Type 1 diabetes mellitus (T1DM) describes a complex group of metabolic disorders
associated with elevated blood glucose levels and increased risks of complications …

Crocin ameliorates oxidative stress and suppresses renal damage in streptozotocin induced diabetic male rats

A Kapucu - Biotechnic & Histochemistry, 2021 - Taylor & Francis
Diabetes mellitus (DM) is a prevalent metabolic disorder with complications including
nephropathy, neuropathy, retinopathy and peripheral vascular disease. Crocin is a water …