Inositols: from established knowledge to novel approaches

S Dinicola, V Unfer, F Facchinetti, CO Soulage… - International Journal of …, 2021 - mdpi.com
Myo-inositol (myo-Ins) and D-chiro-inositol (D-chiro-Ins) are natural compounds involved in
many biological pathways. Since the discovery of their involvement in endocrine signal …

Potential role and therapeutic interests of myo-inositol in metabolic diseases

ML Croze, CO Soulage - Biochimie, 2013 - Elsevier
Several inositol isomers and in particular myo-inositol (MI) and D-chiro-inositol (DCI), were
shown to possess insulin-mimetic properties and to be efficient in lowering post-prandial …

Inositols in insulin signaling and glucose metabolism

A Bevilacqua, M Bizzarri - International journal of …, 2018 - Wiley Online Library
In the past decades, both the importance of inositol for human health and the complex
interaction between glucose and inositol have been the subject of increasing consideration …

Ovulatory and Metabolic Effects of d-Chiro-Inositol in the Polycystic Ovary Syndrome

JE Nestler, DJ Jakubowicz, P Reamer… - … England Journal of …, 1999 - Mass Medical Soc
Background Women with the polycystic ovary syndrome have insulin resistance and
hyperinsulinemia, possibly because of a deficiency of a d-chiro-inositol–containing …

Effects of inositol (s) in women with PCOS: a systematic review of randomized controlled trials

V Unfer, JE Nestler, ZA Kamenov… - International journal …, 2016 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with complex etiology
and pathophysiology, which remains poorly understood. It affects about 5–10% of women of …

Phytochemicals and biofunctional properties of buckwheat: a review

A Ahmed, N Khalid, A Ahmad, NA Abbasi… - The Journal of …, 2014 - cambridge.org
A growing trend for nutraceutical and gluten-free cereal-based products highlights the need
for development of new products. Buckwheat is one of the potential candidates for such …

Effects of myo-inositol in women with PCOS: a systematic review of randomized controlled trials

V Unfer, G Carlomagno, G Dante… - Gynecological …, 2012 - Taylor & Francis
Polycystic ovary syndrome (PCOS) affects 5%–10% of women in reproductive age, and it is
the most common cause of infertility due to ovarian dysfunction and menstrual irregularity …

D‐chiro‐inositol–its functional role in insulin action and its deficit in insulin resistance

J Larner - Journal of Diabetes Research, 2002 - Wiley Online Library
In this review we discuss the biological significance of D‐chiro‐inositol, originally discovered
as a component of a putative mediator of intracellular insulin action, where as a putative …

[HTML][HTML] Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study

MA Niewczas, TL Sirich, AV Mathew, J Skupien… - Kidney international, 2014 - Elsevier
Here we studied plasma metabolomic profiles as determinants of progression to end-stage
renal disease (ESRD) in patients with type 2 diabetes (T2D). This nested case–control study …

Insulin-lowering agents in the management of polycystic ovary syndrome

V De Leo, A La Marca, F Petraglia - Endocrine reviews, 2003 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a medical condition that has brought multiple
specialists together. Gynecologists, endocrinologists, cardiologists, pediatricians, and …