The repair of articular cartilage defects remains a significant challenge in orthopedic
medicine. Hydrogels, three-dimensional polymer networks swollen in water, offer a unique …

Self-assembling peptides are members of a new class of molecules designed for tissue
engineering and protein delivery. Upon injection in a physiological environment, self …

Degenerative disease and damage to articular cartilage represents a growing concern in the
aging population. New strategies for engineering cartilage have employed mesenchymal …

Bone marrow mesenchymal stem cells (BM‐MSCs) and adipose‐derived progenitor cells
(ADPCs) are potential alternatives to autologous chondrocytes for cartilage resurfacing …

Lubricin is a secreted proteoglycan encoded by the Prg4 locus that is abundantly expressed
by superficial zone articular chondrocytes and has been noted to both be sensitive to …

A goal of cartilage tissue engineering is the production of cell-laden constructs possessing
sufficient mechanical and biochemical features to enable native tissue function. This study …

Mesenchymal stem cells (MSCs) are an attractive cell source for cartilage tissue engineering
and regenerative medicine. However, the use of these cells has been limited by their …

Artificial bones have often used for bone regeneration due to their strength, but they cannot
provide an adequate environment for cell penetration and settlement. We therefore …

Graphene-based nanomaterials have been applied as biomaterials to enhance stem cell
adhesion, growth and differentiation by serving as nanocarriers for growth factors or other …

Objective Advanced glycation end-product (AGE) accumulation is implicated in osteoarthritis
(OA) pathogenesis in aging and diabetic populations. Here, we develop a representative …