Therapeutic nanoparticles and their targeted delivery applications

AA Yetisgin, S Cetinel, M Zuvin, A Kosar, O Kutlu - Molecules, 2020 - mdpi.com
Nanotechnology offers many advantages in various fields of science. In this regard,
nanoparticles are the essential building blocks of nanotechnology. Recent advances in …

Immunomodulatory and regenerative effects of mesenchymal stem cells and extracellular vesicles: therapeutic outlook for inflammatory and degenerative diseases

S Dabrowska, A Andrzejewska, M Janowski… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs) are non-hematopoietic, multipotent stem cells derived from
mesoderm, which can be easily isolated from many sources such as bone marrow, umbilical …

Extracellular vesicles in angiogenesis

D Todorova, S Simoncini, R Lacroix, F Sabatier… - Circulation …, 2017 - Am Heart Assoc
During the past decade, extracellular vesicles (EVs), which include apoptotic bodies,
microvesicles, and exosomes, have emerged as important players in cell-to-cell …

Mesenchymal stem cell-derived exosomes as a new therapeutic strategy for liver diseases

G Lou, Z Chen, M Zheng, Y Liu - Experimental & molecular medicine, 2017 - nature.com
The administration of mesenchymal stem cells (MSCs) as a therapy for liver disease holds
great promise. MSCs can differentiate into hepatocytes, reduce liver inflammation, promote …

[PDF][PDF] Liquid biopsy for cancer: circulating tumor cells, circulating free DNA or exosomes?

W Zhang, W Xia, Z Lv, C Ni, Y Xin, L Yang - Cellular Physiology and …, 2017 - karger.com
Precision medicine and personalized medicine are based on the development of
biomarkers, and liquid biopsy has been reported to be able to detect biomarkers that carry …

Development and MPI tracking of novel hypoxia-targeted theranostic exosomes

KO Jung, H Jo, JH Yu, SS Gambhir, G Pratx - Biomaterials, 2018 - Elsevier
Treating the hypoxic region of the tumor remains a significant challenge. The goals of this
study are to develop an exosome platform that can target regions of tumor hypoxia and that …

The role of extracellular vesicles in viral infection and transmission

L Urbanelli, S Buratta, B Tancini, K Sagini, F Delo… - Vaccines, 2019 - mdpi.com
Extracellular vesicles (EVs) have been found to be released by any type of cell and can be
retrieved in every circulating body fluid, namely blood (plasma, serum), saliva, milk, and …

Stem cells-derived exosomes alleviate neurodegeneration and Alzheimer's pathogenesis by ameliorating neuroinflamation, and regulating the associated molecular …

MI Khan, ES Jeong, MZ Khan, JH Shin, JD Kim - Scientific Reports, 2023 - nature.com
Amyloid beta (Aβ) aggregation and tau hyper phosphorylation (p-tau) are key molecular
factors in Alzheimer's disease (AD). The abnormal formation and accumulation of Aβ and p …

Extracellular vesicle-mediated communication within host-parasite interactions

Z Wu, L Wang, J Li, L Wang, Z Wu, X Sun - Frontiers in immunology, 2019 - frontiersin.org
Extracellular vesicles (EVs) are small membrane-surrounded structures released by different
kinds of cells (normal, diseased, and transformed cells) in vivo and in vitro that contain large …

Cardioprotective microRNAs: Lessons from stem cell-derived exosomal microRNAs to treat cardiovascular disease

AS Moghaddam, JT Afshari, SA Esmaeili, E Saburi… - Atherosclerosis, 2019 - Elsevier
The stem cell-based therapy has emerged as a promising therapeutic strategy for treating
cardiovascular ischemic diseases (CVIDs), such as myocardial infarction (MI). However …