16p11. 2 copy number variations and neurodevelopmental disorders
Copy number variations (CNVs) of the human 16p11. 2 genetic locus are associated with a
range of neurodevelopmental disorders, including autism spectrum disorder, intellectual …
range of neurodevelopmental disorders, including autism spectrum disorder, intellectual …
The role of neuropeptide somatostatin in the brain and its application in treating neurological disorders
YH Song, J Yoon, SH Lee - Experimental & Molecular Medicine, 2021 - nature.com
Somatostatin (SST) is a well-known neuropeptide that is expressed throughout the brain. In
the cortex, SST is expressed in a subset of GABAergic neurons and is known as a protein …
the cortex, SST is expressed in a subset of GABAergic neurons and is known as a protein …
Neural circuits regulating prosocial behaviors
Positive, prosocial interactions are essential for survival, development, and well-being.
These intricate and complex behaviors are mediated by an amalgamation of neural circuit …
These intricate and complex behaviors are mediated by an amalgamation of neural circuit …
Neural circuits for social interactions: from microcircuits to input-output circuits
S Xu, M Jiang, X Liu, Y Sun, L Yang, Q Yang… - Frontiers in neural …, 2021 - frontiersin.org
Social behaviors entail responses to social information and requires the perception and
integration of social cues through a complex cognition process that involves attention …
integration of social cues through a complex cognition process that involves attention …
Recent developments in autism genetic research: A scientometric review from 2018 to 2022
Genetic research in Autism Spectrum Disorder (ASD) has progressed tremendously in
recent decades. Dozens of genetic loci and hundreds of alterations in the genetic sequence …
recent decades. Dozens of genetic loci and hundreds of alterations in the genetic sequence …
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11. 2 duplication syndrome by genetic correction of an epilepsy network hub
Neuropsychiatric disorders (NPDs) are frequently co-morbid with epilepsy, but the biological
basis of shared risk remains poorly understood. The 16p11. 2 duplication is a copy number …
basis of shared risk remains poorly understood. The 16p11. 2 duplication is a copy number …
Structural and functional brain alterations revealed by neuroimaging in CNV carriers
Copy Number Variants (CNVs) are associated with elevated rates of neuropsychiatric
disorders. A 'genetics-first'approach, involving the CNV effects on the brain, irrespective of …
disorders. A 'genetics-first'approach, involving the CNV effects on the brain, irrespective of …
Mice lacking melatonin MT2 receptors exhibit attentional deficits, anxiety and enhanced social interaction
DM Thomson, EJ Mitchell… - Journal of …, 2021 - journals.sagepub.com
Background: Aside from regulating circadian rhythms, melatonin also affects cognitive
processes, such as alertness, and modulates the brain circuitry underlying psychiatric …
processes, such as alertness, and modulates the brain circuitry underlying psychiatric …
Increased prevalence of rare copy number variants in treatment-resistant psychosis
Background It remains unknown why~ 30% of patients with psychotic disorders fail to
respond to treatment. Previous genomic investigations of treatment-resistant psychosis have …
respond to treatment. Previous genomic investigations of treatment-resistant psychosis have …
Visual processing in genetic conditions linked to autism: A behavioral study of binocular rivalry in individuals with 16p11. 2 deletions and age‐matched controls
Close phenotypic characterization of individuals with genetic conditions linked to autism
provides a promising approach to navigating the heterogeneity of autism spectrum …
provides a promising approach to navigating the heterogeneity of autism spectrum …