[HTML][HTML] Total neoadjuvant therapy in rectal cancer: the evidence and expectations

B Ludmila, N Alena, S Jaromir, L Radka - Critical Reviews in Oncology …, 2023 - Elsevier
Current management of locally advanced rectal cancer achieves high cure rates, distant
metastatic spread being the main cause of patients' death. Total neoadjuvant therapy (TNT) …

[HTML][HTML] Implications of recent neoadjuvant clinical trials on the future practice of radiotherapy in locally advanced rectal cancer

MK Kang - World Journal of Gastroenterology, 2023 - ncbi.nlm.nih.gov
Over the last two decades, the standard treatment for locally advanced rectal cancer (LARC)
has been neoadjuvant chemoradiotherapy plus total mesorectal excision followed by …

The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of rectal cancer 2023 Supplement

SJ Langenfeld, BR Davis, JD Vogel… - Diseases of the Colon …, 2024 - journals.lww.com
The American Society of Colon and Rectal Surgeons (ASCRS) is dedicated to ensuring
highquality patient care by advancing the science, prevention, and management of …

Clinical complete response in patients with rectal adenocarcinoma treated with short-course radiation therapy and nonoperative management

RI Chin, A Roy, KS Pedersen, Y Huang, SR Hunt… - International Journal of …, 2022 - Elsevier
Purpose This study aimed to determine the clinical efficacy and safety of nonoperative
management (NOM) for patients with rectal cancer with a clinical complete response (cCR) …

Nonoperative management following complete response in rectal cancer after short-course radiation therapy and consolidation chemotherapy: clinical outcomes and …

AV Reddy, B Safar, AY Jia, NS Azad… - American journal of …, 2022 - journals.lww.com
Purpose: The purpose of his study was to report on a cohort of patients managed with
nonoperative management (NOM) with a watch-and-wait strategy after achieving complete …

Current practice patterns in locally advanced rectal cancer at academic institutions: a national survey among radiation oncologists, medical oncologists, and colorectal …

TC Wu, NN Sanford, S Anand, FI Chu, JY Wo… - Clinical colorectal …, 2022 - Elsevier
Purpose To assess the current treatment patterns in locally advanced rectal cancer (LARC)
among radiation oncologists (RO), medical oncologists (MO), and colorectal surgeons (SR) …

A review of circulating tumor DNA as a biomarker guide for total neoadjuvant therapy in patients with locally advanced rectal cancer

J Yahya, M Baber, N Nabavizadeh… - Journal of …, 2023 - Springer
Purpose Non-operative management of patients with locally advanced rectal cancer (LARC)
is emerging as a popular approach for patients that have no evidence of disease following …

The utility of short-course radiotherapy in a watch-and-wait strategy for rectal cancer–the need to measure the interval to tumour response assessment from the …

L Pietrzak, A Cencelewicz, A Rutkowski… - Acta …, 2022 - Taylor & Francis
The watch-and-wait strategy (w&w) is gaining momentum in rectal cancer [1-8]. Most of the
w&w observations come from reports showing the outcomes after neoadjuvant longcourse …

Mild hyperthermia with magnetic resonance-guided high intensity focused ultrasound combined with salvage chemoradiation for recurrent rectal cancer

J Peng, A Partanen, S Pichardo, R Staruch… - International Journal …, 2024 - Taylor & Francis
Introduction Pelvic recurrences from rectal cancer present a challenging clinical scenario.
Hyperthermia represents an innovative treatment option in combination with concurrent …

Cost-effectiveness of total neoadjuvant therapy with short-course radiotherapy for resectable locally advanced rectal cancer

RI Chin, EE Otegbeye, KH Kang, SH Chang… - JAMA Network …, 2022 - jamanetwork.com
Importance Short-course radiotherapy and total neoadjuvant therapy (SCRT-TNT) followed
by total mesorectal excision (TME) has emerged as a new treatment paradigm for patients …