Duchenne muscular dystrophy is a severe, progressive, muscle-wasting disease that leads
to difficulties with movement and, eventually, to the need for assisted ventilation and …

The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …

Nrf2 and its endogenous inhibitor, Keap1, function as a ubiquitous, evolutionarily conserved
intracellular defense mechanism to counteract oxidative stress. Sequestered by cytoplasmic …

Dystrophin is a long rod-shaped protein that connects the subsarcolemmal cytoskeleton to a
complex of proteins in the surface membrane (dystrophin protein complex, DPC), with further …

Highlights•ROS are deliberately produced by the NADPH oxidases in response to specific
physiological stimuli.•The first three-dimensional structure of the NOX catalytic core has …

Reactive oxygen species (ROS) are generated in skeletal muscle both during the rest and
contractile activity. Myogenic cells are equipped with antioxidant enzymes, like superoxide …

Background and Purpose Muscle protein catabolism in patients with diabetic nephropathy
(DN) results in striking loss of muscle proteins, which increases morbidity and mortality risks …

Duchenne muscular dystrophy (DMD) is an X-linked muscle-wasting disease caused by the
loss of dystrophin. DMD is associated with muscle degeneration, necrosis, inflammation …

Significance: Fluorescent protein sensors have revitalized the field of redox biology by
revolutionizing the study of redox processes in living cells and organisms. Recent Advances …

Skeletal muscle atrophy is a pathological condition mainly characterized by a loss of
muscular mass and the contractile capacity of the skeletal muscle as a consequence of …