[HTML][HTML] Circulating microRNAs as emerging regulators of COVID-19

Y Liang, D Fang, X Gao, X Deng, N Chen, J Wu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the novel
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic that …

The role of microRNAs in solving COVID-19 puzzle from infection to therapeutics: A mini-review

S Paul, LAB Vázquez, PR Reyes-Pérez… - Virus Research, 2022 - Elsevier
Nowadays, one of the major global health concerns is coronavirus disease 2019 (COVID-
19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Empagliflozin improves the microRNA signature of endothelial dysfunction in patients with heart failure with preserved ejection fraction and diabetes

P Mone, A Lombardi, U Kansakar, F Varzideh… - … of Pharmacology and …, 2023 - ASPET
Endothelial dysfunction represents a key mechanism underlying heart failure with preserved
ejection fraction (HFpEF), diabetes mellitus (DM), and frailty. However, reliable biomarkers …

Effects of adding L-arginine orally to standard therapy in patients with COVID-19: A randomized, double-blind, placebo-controlled, parallel-group trial. Results of the …

G Fiorentino, A Coppola, R Izzo, A Annunziata… - …, 2021 - thelancet.com
Background We and others have previously demonstrated that the endothelium is a primary
target of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and L …

COVID-19 causes ferroptosis and oxidative stress in human endothelial cells

SS Jankauskas, U Kansakar, C Sardu, F Varzideh… - Antioxidants, 2023 - mdpi.com
Oxidative stress and endothelial dysfunction have been shown to play crucial roles in the
pathophysiology of COVID-19 (coronavirus disease 2019). On these grounds, we sought to …

Cognitive impairment in frail hypertensive elderly patients: role of hyperglycemia

P Mone, J Gambardella, A Pansini, A de Donato… - Cells, 2021 - mdpi.com
Endothelial dysfunction is a key hallmark of hypertension, which is a leading risk factor for
cognitive decline in older adults with or without frailty. Similarly, hyperglycemia is known to …

Exosomal miR-145 and miR-885 regulate thrombosis in COVID-19

J Gambardella, U Kansakar, C Sardu, V Messina… - … of Pharmacology and …, 2023 - ASPET
We hypothesized that exosomal microRNAs could be implied in the pathogenesis of
thromboembolic complications in coronavirus disease 2019 (COVID-19). We isolated …

Cellular miR-150-5p may have a crucial role to play in the biology of SARS-CoV-2 infection by regulating nsp10 gene

SM Akula, P Bolin, PP Cook - RNA biology, 2022 - Taylor & Francis
The role for circulating miRNAs as biomarkers of the COVID-19 disease remains uncertain.
We analysed the circulating miRNA profile in twelve COVID-19 patients with moderate …

Role of neuropilin 1 in COVID-19 patients with acute ischemic stroke

AW Al-Thomali, HM Al-Kuraishy, AI Al-Gareeb… - Biomedicines, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection can trigger
the adaptive and innate immune responses, leading to uncontrolled inflammatory reactions …

Incidence of type 2 diabetes before and during the COVID-19 pandemic in Naples, Italy: a longitudinal cohort study

R Izzo, D Pacella, V Trimarco, MV Manzi… - …, 2023 - thelancet.com
Background The association of COVID-19 with the development of new-onset diabetes has
been recently investigated by several groups, yielding controversial results. Population …