Guanylin, uroguanylin, and the bacterial heat-stable enterotoxin (ST) peptides comprise a
new family of cyclic guanosine 3′-5′ monophosphate (cGMP)-regulating agonists. The …

Disseminated malignancy is the major cause of prostate cancer-related mortality. Circulating
tumor cells (CTCs) are essential for the establishment of metastasis. Various contemporary …

Background High quality genetic material is an essential pre-requisite when analyzing gene
expression using microarray technology. Peripheral blood mononuclear cells (PBMC) are …

Methods of detecting the presence or absence of a class of nucleic acid targets in single
cells through direct or indirect capture of labels to the nucleic acids are provided, where …

Background The colorectal cancer antigen GUCY2C exhibits unique split tolerance, evoking
antigen-specific CD8+, but not CD4+, T-cell responses that deliver anti-tumor immunity …

Nearly half of patients with colorectal cancer (CRC), the third leading cause of cancer deaths
worldwide, are diagnosed in the late stages of the disease. Appropriate treatment is not …

Background: The circulating tumor cells of solid tumors, especially in colorectal cancer has
been of great interest in medical research in the last and new century. Methods: A literature …

Staging patients with colorectal cancer defines their prognosis and therapeutic
management. Unfortunately, histopathology, the current standard for staging, is relatively …

The invention relates to methods of detecting nucleic acids, including methods of detecting
one or more target nucleic acid sequences in multiplex branched-chain DNA assays, are …

AIM: To develop a multiplex reverse transcription polymerase chain reaction (RT-PCR)
method detecting circulating tumor cells in the peripheral blood of colorectal cancer (CRC) …