In physiological hemostasis a prompt recruitment of platelets on the vessel damage prevents
the bleeding by the rapid formation of a platelet plug. Qualitative and/or quantitative platelet …

Although rare, the prevalence of inherited platelet function disorders (IPFD) is probably
underestimated due to under‐diagnosis 1. IPFD are heterogeneous in severity, mechanisms …

Autologous and single‐donor allogenic platelet preparations are increasingly being used in
many areas of regenerative medicine. However, there are few properly controlled …

Platelets play a fundamental role in normal hemostasis, while their inherited or acquired
dysfunctions are involved in a variety of bleeding disorders or thrombotic events. Several …

Platelets are key players in the thrombotic processes. The alterations of platelet function due
to the occurrence of metabolic disorders contribute to an increased trend to thrombus …

Ensuring quality has become a daily requirement in laboratories. In haemostasis, even more
than in other disciplines of biology, quality is determined by a pre-analytical step that …

Platelets have been shown to be associated with pathophysiological processes beyond
thrombosis, demonstrating critical additional roles in homeostatic processes, such as …

Platelets play a major role in hemostasis as ppwell as in many other physiological and
pathological processes. Accordingly, production of about 1011 platelet per day as well as …

Background Diagnosis of inherited platelet function disorders (IPFDs) is important for
appropriate management and to improve epidemiologic and clinical knowledge. However …

Summary Background Ticagrelor, a P2Y 12 antagonist, is an antiplatelet agent approved for
the treatment of acute coronary syndromes; it also inhibits adenosine uptake by erythrocytes …