[HTML][HTML] RNA interference approaches for treatment of HIV-1 infection

ML Bobbin, JC Burnett, JJ Rossi - Genome medicine, 2015 - Springer
HIV/AIDS is a chronic and debilitating disease that cannot be cured with current antiretroviral
drugs. While combinatorial antiretroviral therapy (cART) can potently suppress HIV-1 …

[HTML][HTML] Reduce and control: a combinatorial strategy for achieving sustained HIV remissions in the absence of antiretroviral therapy

R Schwarzer, A Gramatica, WC Greene - Viruses, 2020 - mdpi.com
Human immunodeficiency virus (HIV-1) indefinitely persists, despite effective antiretroviral
therapy (ART), within a small pool of latently infected cells. These cells often display markers …

Gene therapy using RNAi

YL Yang, WT Chang, YW Shih - Gene Therapy-Developments …, 2011 - books.google.com
In the chapter, we hereby provide a brief review about RNA interference (RNAi) and
elucidate its therapeutic applications. The enzymatic synthesis of double-stranded RNA in …

[PDF][PDF] Gene regulation control by RNA

MM Hiz, C Aki - Annals of Biological Research, 2012 - researchgate.net
Evolutionary conserved sequence specific gene regulation mechanism “RNAi” is a powerful
tool for understanding the molecular pathways, genetic screening of desired genes and …

Cell-host interaction: Assessing the role of helper factors in HIV-1 replication

SF Rato - 2010 - search.proquest.com
Much progress has been made in the past twenty-seven years to understand the complexity
of human immunodeficiency virus type 1 (HIV-1) infection and to develop an efficient …

Kontinuierliche, zielgerichtete Evolution hochaffiner Protein-Liganden für Therapie und Prävention am Beispiel des HIV-1 Proteins Rev und seines zellulären …

P Meierhöfer - 2011 - ediss.sub.uni-hamburg.de
Die Suche nach neuen Strategien und Zielen für die Therapie von HIV-Infektionen
konzentriert sich zunehmend auf zelluläre Faktoren, die für die Replikation des Virus …

[PDF][PDF] Regulation of TRIM E3 Ligases and Cyclophilin A and the impact on HIV-1 replication and pathogenesis.

R Singh - 2011 - academia.edu
Regulation of TRIM E3 Ligases and Cyclophilin A and the Impact on HIV-1 Replication and
Pathogenesis Page 1 Regulation of TRIM E3 Ligases and Cyclophilin A and the Impact on HIV-1 …

[PDF][PDF] Kernel Based Off-Target Analysis of Rnai Experiments

KKG Csucs - researchgate.net
The occurrence of off-target effects is still a challenging aspect in the interpretation of data
from largescale RNA interference screens. Up to now many methods have been found to …

[引用][C] Gene therapy using RNAi

Y Yu-Lin, C Wen-Teng, S Yuan-Wei - 2011