Axonal and presynaptic FMRP: Localization, signal, and functional implications

X Wang, D Sela-Donenfeld, Y Wang - Hearing research, 2023 - Elsevier
Fragile X mental retardation protein (FMRP) binds a selected set of mRNAs and proteins to
guide neural circuit assembly and regulate synaptic plasticity. Loss of FMRP is responsible …

Peripheral Fragile X messenger ribonucleoprotein is required for the timely closure of a critical period for neuronal susceptibility in the ventral cochlear nucleus

X Yu, Y Wang - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Alterations in neuronal plasticity and critical periods are common across
neurodevelopmental diseases, including Fragile X syndrome (FXS), the leading single-gene …

[图书][B] FMRP Mechanism of Circuit Development and Dynamics in the Auditory Brainstem

X Yu - 2022 - search.proquest.com
Fragile X syndrome (FXS) is a leading monogenetic cause of intellectual disability and
autism. It is caused by transcriptional silencing of the FMR1 gene and the resultant loss of its …