Objective To investigate, by systematically reviewing the literature, whether the attention-
deficit/hyperactivity disorder (ADHD) polygenic risk score (PRS) associates with ADHD and …

Bipolar disorder (BD) is a highly heritable mental disorder and is estimated to affect about 50
million people worldwide. Our understanding of the genetic etiology of BD has greatly …

Polygenic risk scores (PRSs) have become an increasingly popular approach for
demonstrating polygenic influences on complex traits and for establishing common …

Objective: Attention deficit hyperactivity disorder is a frequent comorbid condition in adults
with bipolar disorder. We performed a meta-analysis aimed at assessing sociodemographic …

Early identification of attention-deficit/hyperactivity disorder (ADHD) is critical for mitigating
the many negative functional outcomes associated with its diagnosis. Because of the strong …

Objective We conducted a systematic review of studies using molecular genetics and
statistical approaches to investigate the role of common genetic variation in the …

Background It remains unclear how adverse childhood experiences (ACE) and increased
genetic risk for bipolar disorder (BD) interact to influence BD symptom outcomes. Here we …

Response to lithium varies widely between individuals with bipolar disorder (BD). Polygenic
risk scores (PRSs) can uncover pharmacogenomics effects and may help predict drug …

Objective: Hospital care due to severe mood episodes are consequences for many but not
all 29 persons with bipolar disorder. Likewise, some but not all patients suffer long-term 30 …

Background Bipolar Disorder (BD) is a complex disease. It is heterogeneous, both at the
phenotypic and genetic level, although the extent and impact of this heterogeneity is not fully …