The insulin-like growth factor (IGF) system comprises multiple growth factor receptors,
including insulin-like growth factor 1 receptor (IGF-1R), insulin receptor (IR)-A and-B. These …

The insulin receptor (IR) is a (αβ) 2-type transmembrane tyrosine kinase that plays a central
role in cell metabolism. Each αβ heterodimer consists of an extracellular ligand-binding α …

Maintaining pH homeostasis is vital for all mammalian cells since hydrogen and hydroxyl
ions perform important functions in the regulation of metabolism. Today, it is believed that …

ErbB2 is an oncogene receptor tyrosine kinase linked to breast cancer. It is a member of the
epidermal growth factor receptor (EGFR) minifamily. ErbB2 is currently viewed as an orphan …

Insulin receptor–related receptor (IRR) is a receptor tyrosine kinase of the insulin receptor
family and functions as an extracellular alkali sensor that controls metabolic alkalosis in the …

The insulin receptor-related receptor (IRR) is a cellular sensor of a weakly alkaline medium.
Its spatial structure and the mechanism of activation have not been yet established. In the …

The insulin receptor-related receptor (IRR) is the only known metabotropic sensor of
extracellular alkaline medium involved in the regulation of the acid–base balance in the …

The orphan insulin receptor-related receptor (IRR), in contrast to its close homologs, the
insulin receptor (IR) and insulin-like growth factor receptor (IGF-IR) can be activated by …

The insulin receptor-related receptor (IRR) is a receptor tyrosine kinase and a close
homologue of the insulin receptor and the insulin-like growth factor receptor; however …

Рецептор, подобный рецептору инсулина (IRR, Insulin receptor-related receptor),
является единственным известным на сегодняшний день метаботропным сенсором …