Organic electrochemical neurons and synapses with ion mediated spiking

PC Harikesh, CY Yang, D Tu, JY Gerasimov… - Nature …, 2022 - nature.com
Future brain-machine interfaces, prosthetics, and intelligent soft robotics will require
integrating artificial neuromorphic devices with biological systems. Due to their poor …

Regulation of the JAK/STAT signaling pathway in spinal cord injury: an updated review

X Guo, C Jiang, Z Chen, X Wang, F Hong… - Frontiers in …, 2023 - frontiersin.org
Cytokines are involved in neural homeostasis and pathological processes associated with
neuroinflammation after spinal cord injury (SCI). The biological effect of cytokines, including …

[HTML][HTML] Stem cell-derived neuronal relay strategies and functional electrical stimulation for treatment of spinal cord injury

BQ Lai, X Zeng, WT Han, MT Che, Y Ding, G Li… - Biomaterials, 2021 - Elsevier
The inability of adult mammals to recover function lost after severe spinal cord injury (SCI)
has been known for millennia and is mainly attributed to a failure of brain-derived nerve fiber …

A biohybrid synapse with neurotransmitter-mediated plasticity

ST Keene, C Lubrano, S Kazemzadeh, A Melianas… - Nature Materials, 2020 - nature.com
Brain-inspired computing paradigms have led to substantial advances in the automation of
visual and linguistic tasks by emulating the distributed information processing of biological …

Emergence of epidural electrical stimulation to facilitate sensorimotor network functionality after spinal cord injury

JS Calvert, PJ Grahn, KD Zhao, KH Lee - Neuromodulation: Technology at …, 2019 - Elsevier
Background Traumatic spinal cord injury (SCI) disrupts signaling pathways between the
brain and spinal networks below the level of injury. In cases of severe SCI, permanent loss …

Clinical opportunities for continuous biosensing and closed-loop therapies

J Li, JY Liang, SJ Laken, R Langer, G Traverso - Trends in Chemistry, 2020 - cell.com
Continuous glucose monitors (CGMs) and closed-loop drug delivery systems have
revolutionized patient care in diabetes and anesthesia. Here, we review the current state of …

Highly bionic neurotransmitter-communicated neurons following integrate-and-fire dynamics

S Luo, L Shao, D Ji, Y Chen, X Wang, Y Wu… - Nano Letters, 2023 - ACS Publications
In biological neural networks, chemical communication follows the reversible integrate-and-
fire (I&F) dynamics model, enabling efficient, anti-interference signal transport. However …

Systematic analysis of wavelet denoising methods for neural signal processing

G Baldazzi, G Solinas, J Del Valle… - Journal of Neural …, 2020 - iopscience.iop.org
Objective. Among the different approaches for denoising neural signals, wavelet-based
methods are widely used due to their ability to reduce in-band noise. All wavelet denoising …

Multifunctional soft implants to monitor and control neural activity in the central and peripheral nervous system: a review

Z Fekete, A Pongrácz - Sensors and Actuators B: Chemical, 2017 - Elsevier
The development of neural implants is seeking minimally invasive approaches by utilizing
novel polymer substrates and integration concepts to interface the living tissue. In the recent …

Intraspinal microstimulation produces over-ground walking in anesthetized cats

BJ Holinski, KA Mazurek, DG Everaert… - Journal of neural …, 2016 - iopscience.iop.org
Objective. Spinal cord injury causes a drastic loss of motor, sensory and autonomic function.
The goal of this project was to investigate the use of intraspinal microstimulation (ISMS) for …