Conditions such as acute pancreatitis, ulcerative colitis, delayed graft function and infections
caused by a variety of microorganisms, including gram-positive and gram-negative …

Abstract α1-Antitrypsin (AAT), a serine protease inhibitor, is the third most abundant protein
in plasma. Although the best-known function of AAT is irreversible inhibition of elastase, AAT …

Roles for the baculoviral inhibitor of apoptosis repeat-containing (BIRC) genes, BIRC2 and
BIRC3, may include signaling to the inflammatory transcription factor, nuclear factor-κB (NF …

While IκB-kinase-ε (IKKε) induces immunomodulatory genes following viral stimuli, its up-
regulation by inflammatory cytokines remains under-explored. Since airway epithelial cells …

Glucocorticoids act via the glucocorticoid receptor (GR; NR3C1) to downregulate
inflammatory gene expression and are effective treatments for mild to moderate asthma …

Glucocorticoids are widely used in the treatment of allergic and inflammatory diseases.
Glucocorticoids have a widespread action on gene expression resulting in their …

Tuberculosis (TB) is the deadliest disease caused by a bacterial agent. Glucocorticoids
(GCs) have a typical anti-inflammatory effect, but recently it has been shown that they can …

Air pollution is a pervasive and global problem, with 99% of the world's population living in
areas that exceed the World Health Organization exposure guidelines. Although public …