The PC12 cell line is one of the most commonly used in neuroscience research, including
studies on neurotoxicity, neuroprotection, neurosecretion, neuroinflammation, and …

Peripheral nerve injury results in significant sensory and motor functional deficits. Although
direct neurorrhaphy in the early phase may reduce its devastating effects, direct end-to-end …

Depression, a mental illness that is receiving increasing attention, is caused by multiple
factors and genes and adversely affects social life and health. Several hypotheses have …

A challenge in current stem cell therapies for Parkinson's disease (PD) is controlling
neuronal outgrowth from the substantia nigra towards the targeted area where connectivity …

The regeneration of injured spinal cord is hampered by the lack of vascular supply and
neurotrophic support. Transplanting tissue‐engineered constructs with developed vascular …

Background Substantial evidence supports the use of inexpensive β-AR antagonists (beta
blockers) against a variety of cancers, and the β-AR antagonist propranolol was recently …

Breast cancer is the most frequently diagnosed cancer among women worldwide. Here,
recombinant human lactoferrin (rhLf) expressed in Pichia pastoris was tested for its potential …

Aligned sub-micron fibres are an outstanding surface for orienting and promoting neurite
outgrowth; therefore, attractive features to include in peripheral nerve tissue scaffolds. A new …

Nowdays, neurodegenerative diseases represent a great challenge from both the
therapeutic and diagnostic points of view. Indeed, several physiological barriers of the body …

Dental pulp stem cells (DPSCs) secrete neurotrophic factors which may play an important
therapeutic role in neural development, maintenance and repair. To test this hypothesis …