Chronic inflammation in adipose tissue, possibly related to adipose cell hypertrophy,
hypoxia, and/or intestinal leakage of bacteria and their metabolic products, likely plays a …

Ovarian cancer is the most lethal gynecological malignancy worldwide. Most patients are
diagnosed at late stages because of atypical symptoms and the lack of effective early …

Macrophages are traditional innate immune cells that play critical roles in the clearance of
pathogens and the maintenance of tissue homeostasis. Accumulating evidence proves that …

Stromal immune cells constitute the tumor microenvironment. These immune cell subsets
include myeloid cells, the so-called tumor-associated myeloid cells (TAMCs), which are of …

Nutritional status is critically important for immune cell function. While obesity is
characterized by inflammation that promotes metabolic syndrome including cardiovascular …

Obesity is characterized by adipose tissue inflammation. Because proteoglycans regulate
inflammation, here we investigate their role in adipose tissue inflammation in obesity. We …

Obesity is now recognised as a low grade, chronic inflammatory disease that is linked to a
myriad of disorders including cancer, cardiovascular disease and type 2 diabetes (T2D) …

Hepatocellular carcinoma (HCC) is one of the most common digestive system cancers
(DSCs) with a poor prognosis. Zinc‐regulated transporter (ZRT)/iron‐regulated transporter …

Thyroid cancer is the most common cancer in the endocrine system. Most thyroid cancers
have good prognosis, but some of them are resistant to treatment or show aggressive …

Low-grade inflammation links obesity to insulin resistance through the activation of tissue-
infiltrating immune cells. Interleukin-6 (IL-6) is a crucial regulator of T cells and is increased …