Understanding testicular single cell transcriptional atlas: from developmental complications to male infertility

MB Tirumalasetty, I Bhattacharya… - Frontiers in …, 2024 - frontiersin.org
Spermatogenesis is a multi-step biological process where mitotically active diploid (2n)
spermatogonia differentiate into haploid (n) spermatozoa via regulated meiotic …

[HTML][HTML] Seminal exosomes–an important biological marker for various disorders and syndrome in human reproduction

AS Vickram, PS Srikumar, S Srinivasan… - Saudi journal of …, 2021 - Elsevier
Background Exosomes are nano-sized membrane vesicles, secreted by different types of
cells into the body's biological fluids. They are found in abundance in semen as compared to …

Etiology of male infertility: an update

I Bhattacharya, SS Sharma, SS Majumdar - Reproductive Sciences, 2024 - Springer
Spermatogenesis is a complex process of germ cell division and differentiation that involves
extensive cross-talk between the developing germ cells and the somatic testicular cells …

Revisiting the gonadotropic regulation of mammalian spermatogenesis: evolving lessons during the past decade

I Bhattacharya, S Dey, A Banerjee - Frontiers in Endocrinology, 2023 - frontiersin.org
Spermatogenesis is a multi-step process of male germ cell (Gc) division and differentiation
which occurs in the seminiferous tubules of the testes under the regulation of gonadotropins …

Follicle-stimulating hormone-mediated decline in miR-92a-3p expression in pubertal mice Sertoli cells is crucial for germ cell differentiation and fertility

A Gupta, A Vats, A Ghosal, K Mandal, R Sarkar… - Cellular and Molecular …, 2022 - Springer
Sertoli cells (Sc) are the sole target of follicle-stimulating hormone (FSH) in the testis and
attain functional maturation post-birth to significantly augment germ cell (Gc) division and …

A systematic review of interventions to improve male knowledge of fertility and fertility-related risk factors

S Krishnan, MP Daly, R Kipping, C Harrison - Human Fertility, 2024 - Taylor & Francis
Male infertility is a global health concern. The effectiveness of interventions developed to
improve males' knowledge of fertility regulation and fertility-related risk factors remains …

Declining levels of miR-382-3p at puberty trigger the onset of spermatogenesis

A Gupta, K Mandal, P Singh, R Sarkar… - … Therapy-Nucleic Acids, 2021 - cell.com
A major change in the transcriptome of testicular Sertoli cells (Scs) at the onset of puberty
enables them to induce robust spermatogenesis. Through comprehensive literature mining …

Pubertal orchestration of hormones and testis in primates

I Bhattacharya, S Sen Sharma… - Molecular …, 2019 - Wiley Online Library
The term “Puberty”, socially known as “Adolescence” is the transitional period from juvenile
life to adulthood with functional maturation of gonads and genital organs. In this process …

Hormone induced differential transcriptome analysis of Sertoli cells during postnatal maturation of rat testes

M Gautam, I Bhattacharya, U Rai, SS Majumdar - PloS one, 2018 - journals.plos.org
Sertoli cells (Sc) are unique somatic cells of testis that are the target of both FSH and
testosterone (T) and regulate spermatogenesis. Although Sc of neonatal rat testes are …

Dickkopf Homolog 3 (DKK3) Plays a Crucial Role Upstream of WNT/β-CATENIN Signaling for Sertoli Cell Mediated Regulation of Spermatogenesis

DS Das, N Wadhwa, N Kunj, K Sarda, BS Pradhan… - PLoS …, 2013 - journals.plos.org
Testicular Sertoli cells (Sc) are main somatic component of seminiferous tubules that govern
the differentiation of germ cells (Gc) and provide them physical support. Sc are the target of …