The ICSI procedure from past to future: a systematic review of the more controversial aspects

P Rubino, P Viganò, A Luddi… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND ICSI is currently the most commonly used assisted reproductive technology,
accounting for 70–80% of the cycles performed. This extensive use, even excessive, is partly …

Sperm selection in natural conception: what can we learn from Mother Nature to improve assisted reproduction outcomes?

D Sakkas, M Ramalingam, N Garrido… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND In natural conception only a few sperm cells reach the ampulla or the site of
fertilization. This population is a selected group of cells since only motile cells can pass …

Sperm capacitation: a distant landscape glimpsed but unexplored

RJ Aitken, B Nixon - Molecular human reproduction, 2013 - academic.oup.com
Capacitation is a remarkable process whereby spermatozoa prepare themselves for
engagement with the oocyte. Although the existence of this process has been appreciated …

[HTML][HTML] “Physiologic ICSI”: hyaluronic acid (HA) favors selection of spermatozoa without DNA fragmentation and with normal nucleus, resulting in improvement of …

L Parmegiani, GE Cognigni, S Bernardi, E Troilo… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To evaluate the role of hyaluronic acid (HA) for sperm selection before
intracytoplasmic sperm injection (ICSI). DESIGN: Three prospective studies. SETTING …

Sperm processing for advanced reproductive technologies: Where are we today?

KL Rappa, HF Rodriguez, GC Hakkarainen… - Biotechnology …, 2016 - Elsevier
Assisted reproductive technologies (ARTs) utilize sperm sorting methods to select viable
sperm from the semen samples. Conventional sperm sorting techniques in current use are …

Magnetic micromotors for multiple motile sperm cells capture, transport, and enzymatic release

H Xu, M Medina‐Sánchez… - Angewandte Chemie …, 2020 - Wiley Online Library
An integrated system combining a magnetically‐driven micromotor and a synthetized protein‐
based hyaluronic acid (HA) microflake is presented for the in situ selection and transport of …

Simulating nature in sperm selection for assisted reproduction

ETY Leung, CL Lee, X Tian, KKW Lam, RHW Li… - Nature Reviews …, 2022 - nature.com
Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …

Rapid selection of sperm with high DNA integrity

R Nosrati, M Vollmer, L Eamer, MC San Gabriel… - Lab on a Chip, 2014 - pubs.rsc.org
Sperm selection is essential to assisted reproductive technology (ART), influencing
treatment outcomes and the health of offspring. The fundamental challenge of sperm …

[HTML][HTML] Human sperm DNA fragmentation and its correlation with conventional semen parameters

E Evgeni, K Charalabopoulos… - Journal of reproduction …, 2014 - ncbi.nlm.nih.gov
Background The initial step in the diagnostic investigation of male infertility has been
traditionally based on the conventional seminal profile. However, there are significant …

Sperm selection methods in the 21st century

DA Vaughan, D Sakkas - Biology of reproduction, 2019 - academic.oup.com
Natural sperm selection in humans is a rigorous process resulting in the highest quality
sperm reaching, and having an opportunity to fertilize, the oocyte. Relative to other …