Membrane-enveloped viruses are a leading cause of viral epidemics, and there is an
outstanding need to develop broad-spectrum antiviral strategies to treat and prevent …

In recent years, lipopeptides (LPs) have attracted a lot of attention in the pharmaceutical
industry due to their broad-spectrum of antimicrobial activity against a variety of pathogens …

Host defense peptides (HDPs) represent an alternative way to address the emergence of
antibiotic resistance. Crocodylians are interesting species for the study of these molecules …

Membrane-active peptides (MAPs) have several potential therapeutic uses, including as
antimicrobial drugs. Many traditional methods used to evaluate the membrane interactions …

Lipophilic carbocyanine dyes are widely used as fluorescent cell membrane probes in
studies ranging from biophysics to cell biology. While they are extremely useful for …

The oral bioavailability of therapeutic peptides is generally low. To increase peptide
transport across the gastrointestinal barrier, permeation enhancers are often used. Despite …

Antitumor peptides may potentially alleviate the problem of chemoresistance but do not yet
target tumor cells and would be cytotoxic to normal cells. Here, we designed a pH-activated …

Transmembrane peptides contain polar residues in the interior of the membrane, which may
alter the electrostatic environment and favor hydration in the otherwise nonpolar …

Most research employing liposomes as membrane model systems or drug delivery carriers
relies on bulk read-out techniques and thus intrinsically assumes all liposomes of the …

There is considerable interest in understanding the interactions of antimicrobial peptides
with phospholipid membranes. Fluorescence correlation spectroscopy (FCS) is a powerful …