Understanding the physical and chemical nature of the warfarin drug binding site in human serum albumin: experimental and theoretical studies
O K. Abou-Zied - Current Pharmaceutical Design, 2015 - benthamdirect.com
Human serum albumin (HSA) is one of the major carrier proteins in the body and constitutes
approximately half of the protein found in blood plasma. It plays an important role in lipid …
approximately half of the protein found in blood plasma. It plays an important role in lipid …
Photophysical properties of hydroxyphenyl benzazoles and their applications as fluorescent probes to study local environment in DNA, protein and lipid
SAJ Sulaiman, GS Al‐Rasbi, OK Abou‐Zied - Luminescence, 2016 - Wiley Online Library
Fluorescence techniques have drawn increasing attention because they provide crucial
information about molecular interactions in protein–ligand systems beyond that obtained by …
information about molecular interactions in protein–ligand systems beyond that obtained by …
Comparison of Complexation-Induced pKa Shifts in the Ground and Excited States of Dyes as Well as Different Macrocyclic Hosts and Their Manifestation in Host …
1-Aminopyrene and 1-naphthylamine-5-sulfonic acid were converted to the putrescine (1, 4-
diaminobutane)-substituted derivatives (dyes 1 and 2). The diaminobutyl anchor serves as a …
diaminobutane)-substituted derivatives (dyes 1 and 2). The diaminobutyl anchor serves as a …
Simultaneous binding of folic acid and methotrexate to human serum albumin: insights into the structural changes of protein and the location and competitive …
Protein structure can be flexible to adopt multiple conformations to house small molecules.
In this paper, we have attempted to experimentally figure out how the structure of a transport …
In this paper, we have attempted to experimentally figure out how the structure of a transport …
[HTML][HTML] Effects of perfluorooctane sulfonate on the conformation and activity of bovine serum albumin
Y Wang, H Zhang, Y Kang, J Cao - Journal of Photochemistry and …, 2016 - Elsevier
Perfluorooctane sulfonate (PFOS) is among the most prominent contaminates in human
serum and has been reported to possess potential toxicity to the human body. In this study …
serum and has been reported to possess potential toxicity to the human body. In this study …
Detailed scrutiny of the anion receptor pocket in subdomain IIA of serum proteins toward individual response to specific ligands: HSA-pocket resembles flexible …
Present study reveals that the subdomain IIA cavity of two homologous serum albumins
(HSA, BSA) has inherent mutual structural and functional deviations which render noticeable …
(HSA, BSA) has inherent mutual structural and functional deviations which render noticeable …
Analytical aspects of achiral and cyclodextrin-mediated capillary electrophoresis of warfarin and its two main derivatives assisted by theoretical modeling
P Nowak, M Garnysz, MP Mitoraj, F Sagan… - … of Chromatography A, 2015 - Elsevier
Several distinct analytical issues have been addressed by performing capillary
electrophoresis-based separations of the warfarin, 7-hydroxywarfarin and 10 …
electrophoresis-based separations of the warfarin, 7-hydroxywarfarin and 10 …
Modulation of p K a by cyclodextrins; subtle structural changes induce spectacularly different behaviors
PM Nowak, M Woźniakiewicz, MP Mitoraj, M Garnysz… - RSC …, 2015 - pubs.rsc.org
Tuning of acidity-related properties by host–guest complexation is one of the most promising
concepts in current supramolecular chemistry. However, still little is known about structural …
concepts in current supramolecular chemistry. However, still little is known about structural …
[HTML][HTML] Probing the binding interaction of human serum albumin with three bioactive constituents of Eriobotrta japonica leaves: Spectroscopic and molecular …
Q Wang, Q Sun, X Ma, Z Rao, H Li - Journal of Photochemistry and …, 2015 - Elsevier
Corosolic acid (CRA), maslinic acid (MA), and tormentic acid (TA) are three kind of bioactive
constituents of Eriobotrta japonica leaves. In this study, plasma protein binding model …
constituents of Eriobotrta japonica leaves. In this study, plasma protein binding model …
Host-guest complexes of imazalil with cucurbit [8] uril and β-cyclodextrin and their effect on plant pathogenic fungi
We report the control of imazalil (IMZ) antifungal activity utilizing its non-covalent assembly
with β-cyclodextrins (β-CD) and cucurbit [8] uril (CB8) macrocycles, as well as its stimuli …
with β-cyclodextrins (β-CD) and cucurbit [8] uril (CB8) macrocycles, as well as its stimuli …