Sex, stroke, and inflammation: the potential for estrogen-mediated immunoprotection in stroke

RM Ritzel, LA Capozzi, LD McCullough - Hormones and behavior, 2013 - Elsevier
This article is part of a Special Issue" Hormones & Neurotrauma". Stroke is the third leading
cause of death and the primary cause of disability in the developed world. Experimental and …

Mammographic density, response to hormones, and breast cancer risk

NF Boyd, O Melnichouk, LJ Martin, G Hislop… - Journal of Clinical …, 2011 - ascopubs.org
Background Percent mammographic density (PMD) is a strong risk factor for breast cancer
that changes in response to changes in hormone exposure. We have examined the …

A novel estrogen receptor-microRNA 190a-PAR-1-pathway regulates breast cancer progression, a finding initially suggested by genome-wide analysis of loci …

HW Chu, CW Cheng, WC Chou, LY Hu… - Human molecular …, 2014 - academic.oup.com
To identify microRNAs that are important in regulating breast cancer progression, the
present study used data for the 199 961 single-nucleotide polymorphisms (SNPs) in 837 …

Evaluation of breast cancer susceptibility using improved genetic algorithms to generate genotype SNP barcodes

CH Yang, YD Lin, LY Chuang… - IEEE/ACM transactions …, 2013 - ieeexplore.ieee.org
Genetic association is a challenging task for the identification and characterization of genes
that increase the susceptibility to common complex multifactorial diseases. To fully execute …

mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer

S von der Heyde, S Wagner, A Czerny, M Nietert… - PloS one, 2015 - journals.plos.org
Intrinsic and acquired resistance to the monoclonal antibody drug trastuzumab is a major
problem in the treatment of HER2-positive breast cancer. A deeper understanding of the …

An improved PSO algorithm for generating protective SNP barcodes in breast cancer

LY Chuang, YD Lin, HW Chang, CH Yang - PLoS One, 2012 - journals.plos.org
Background Possible single nucleotide polymorphism (SNP) interactions in breast cancer
are usually not investigated in genome-wide association studies. Previously, we proposed a …

The inhibitory role of miR-486-5p on CSC phenotype has diagnostic and prognostic potential in colorectal cancer

A Pisano, C Grinan-Lison, C Farace, G Fiorito, G Fenu… - Cancers, 2020 - mdpi.com
Simple Summary Colorectal cancer is nowadays one of the most diffuse cancers worldwide.
Its early diagnosis is often linked with a positive outcome. However, colorectal cancer is a …

A Meta-Analysis of the Association between ESR1 Genetic Variants and the Risk of Breast Cancer

T Li, J Zhao, J Yang, X Ma, Q Dai, H Huang, L Wang… - PloS one, 2016 - journals.plos.org
Background Single nucleotide polymorphisms (SNPs) in the estrogen receptor gene (ESR1)
play critical roles in breast cancer (BC) susceptibility. Genome-wide association studies …

Alteration of miRNA-mRNA interactions in lymphocytes of individuals with schizophrenia

MP Geaghan, JR Atkins, AM Brichta, PA Tooney… - Journal of Psychiatric …, 2019 - Elsevier
The aetiology of schizophrenia is complex, heterogeneous, and involves interplay of many
genetic and environmental influences. While significant progress has been made in the …

A possible link of genetic variations in ER/IGF1R pathway and risk of melanoma

TA Yuan, V Yourk, A Farhat, KL Guo, A Garcia… - International Journal of …, 2020 - mdpi.com
The mechanism of gender disparity in cutaneous melanoma incidence remains unclear.
Steroid hormones including estrogens have long been implicated in the course of …