[PDF][PDF] Adverse effects of nonsteroidal antiinflammatory drugs: an update of gastrointestinal, cardiovascular and renal complications

S Harirforoosh, W Asghar… - Journal of Pharmacy & …, 2013 - frontierspartnerships.org
Non-steroidal anti-inflammatory drugs (NSAIDs) are used chronically to reduce pain and
inflammation in patients with arthritic conditions, and also acutely as analgesics by many …

Quality assessment of observational studies in a drug-safety systematic review, comparison of two tools: the Newcastle–Ottawa scale and the RTI item bank

AV Margulis, M Pladevall, N Riera-Guardia… - Clinical …, 2014 - Taylor & Francis
Background The study objective was to compare the Newcastle–Ottawa Scale (NOS) and
the RTI item bank (RTI-IB) and estimate interrater agreement using the RTI-IB within a …

Individual NSAIDs and upper gastrointestinal complications: a systematic review and meta-analysis of observational studies (the SOS project)

J Castellsague, N Riera-Guardia, B Calingaert… - Drug safety, 2012 - Springer
Background: The risk of upper gastrointestinal (GI) complications associated with the use of
NSAIDs is a serious public health concern. The risk varies between individual NSAIDs; …

Adverse effects of analgesics commonly used by older adults with osteoarthritis: focus on non-opioid and opioid analgesics

CK O'Neil, JT Hanlon, ZA Marcum - The American journal of geriatric …, 2012 - Elsevier
BACKGROUND: Osteoarthritis (OA) is the most common cause of disability in older adults,
and although analgesic use can be helpful, it can also result in adverse drug events …

Non‐steroidal anti‐inflammatory drug‐induced cardiovascular adverse events: a meta‐analysis

BR Gunter, KA Butler, RL Wallace… - Journal of clinical …, 2017 - Wiley Online Library
What is known and objective Although non‐steroidal anti‐inflammatory drugs (NSAID s)
have been studied in randomized, controlled trials and meta‐analyses in an effort to …

Myocardial infarction and individual nonsteroidal anti‐inflammatory drugs meta‐analysis of observational studies

C Varas‐Lorenzo, N Riera‐Guardia… - … and drug safety, 2013 - Wiley Online Library
Objective To conduct a systematic review of observational studies on the risk of acute
myocardial infarction (AMI) with use of individual nonsteroidal anti‐inflammatory drugs …

Non-steroidal anti-inflammatory drug (NSAID) therapy in patients with hypertension, cardiovascular, renal or gastrointestinal comorbidities: joint APAGE/APLAR …

CC Szeto, K Sugano, JG Wang, K Fujimoto, S Whittle… - Gut, 2020 - gut.bmj.com
Background Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly
prescribed medications, but they are associated with a number of serious adverse effects …

Novel anti-inflammatory and analgesic agents: synthesis, molecular docking and in vivo studies

DI Ugwu, UC Okoro, PO Ukoha, A Gupta… - Journal of enzyme …, 2018 - Taylor & Francis
Twelve new derivatives of benzothiazole bearing benzenesulphonamide and carboxamide
were synthesised and investigated for their in vivo anti-inflammatory, analgesic and …

Cardiovascular and cerebrovascular risk with nonsteroidal anti-inflammatory drugs and cyclooxygenase 2 inhibitors: latest evidence and clinical implications

A Fanelli, D Ghisi, PL Aprile… - Therapeutic advances in …, 2017 - journals.sagepub.com
Observational studies and meta-analyses have shown that the administration of
nonsteroidal anti-inflammatory drugs (NSAIDs), especially when prescribed at high doses …

High-risk use of over-the-counter non-steroidal anti-inflammatory drugs: a population-based cross-sectional study

AR Koffeman, VE Valkhoff, S Çelik, G W't Jong… - British Journal of …, 2014 - bjgp.org
Background The use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with
serious adverse drug events (ADEs). Aim To determine the prevalence of over-the-counter …